A study suggests that tests to grade and stage prostate cancer underestimated the severity of the disease in half of men whose cancers had been classified as ‘slow growing’. This highlights the urgent need for better tests to define how aggressive a prostate cancer is from the outset. Scientists from the University of Cambridge compared […]
A research team lead by Academy Professor Kari Rissanen at the University of Jyväskylä has discovered a new water-soluble fluorescent detection system that is extremely sensitive to pyrophosphate (PPi). Pyrophosphate has a key role in energy transduction, DNA replication and other metabolic processes that are dysregulated in cancer cells. The discovery might lead to the […]
Scientists have known that abnormal brain growth is associated with autism spectrum disorder. However, the relationship between the two has not been well understood. Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that mutations in a specific gene that is disrupted in some individuals with autism results in too […]
Case Western Reserve researchers have discovered that a protein previously implicated in disease plays such a positive role in learning and memory that it may someday contribute to cures of cognitive impairments. The findings regarding the potential virtues of fatty acid binding protein 5 (FABP5) — usually associated with cancer and psoriasis. ‘Overall, our data […]
Siemens Healthcare Diagnostics has become the first manufacturer to gain standardization of its ADVIA Centaur Vitamin D Total assay to the National Institute of Standards and Technology – Ghent University Reference Measurement Procedure based on isotope-dilution liquid chromatography-tandem mass spectrometry. The Vitamin D Standardization Programme (VDSP) was established in 2010 and stated that all manufacturers […]
During breast-tissue development, a transcription factor called SLUG plays a role in regulating stem cell function and determines whether breast cells will mature into luminal or basal cells. Studying factors, such as SLUG, that regulate stem-cell activity and breast-cell identity are important for understanding how breast tumours arise and develop into different subtypes. Ultimately, this […]
Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer’s disease without ever showing clinical symptoms in their lifetime. Vanderbilt University Medical Center memory researchers have discovered a potential genetic variant in these asymptomatic individuals that may make brains more resilient against Alzheimer’s. ‘Most Alzheimer’s research is searching for genes that predict […]
Dartmouth Institute for Quantitative Biomedical Sciences (iQBS) researchers developed a new gene expression analysis approach for identifying cancer genes. The study results challenge the current paradigm of microarray data analysis and suggest that the new method may improve identification of cancer-associated genes. Typical microarray-based gene expression analyses compare gene expression in adjacent normal and cancerous […]
Women with high levels of a common liver enzyme measured prior to pregnancy were twice as likely to subsequently develop gestational diabetes than those with the lowest levels, according to a Kaiser Permanente study. The liver plays an important role in regulating glucose levels in the body. The liver enzyme, called gamma-glutamyl transferase (known as […]
EKF Diagnostics has acquired Separation Technology, Inc. (STI), the Florida based manufacturer of in vitro diagnostics devices for hematology testing from Thermo Fisher Scientific, Inc. This acquisition complements EKF’s existing offering in the hemoglobin testing market place, which includes Hemo Control (also sold as HemoPoint H2 in USA and Asia). Notably, STI’s primary instrument is […]
November 2024
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