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Author Archive for: 3wmedia
Entries by 3wmedia
Call for action on diabetes
This year’s annual World Health Day on 7th April highlighted the dramatic rise in the prevalence of Type 2 diabetes (T2DM) and urged global action to contain the epidemic. The number of people suffering from T2DM has approximately quadrupled in three and a half decades; currently 8.5% of the global adult population is affected. Because […]
The clinical chemistry laboratory in the diagnosis and management of testicular cancer
Cancer of the testicles, primarily the germ cells, is a highly treatable disease common to young men. This article describes how chemical biomarkers are central to the diagnosis, characterization, therapeutic monitoring, prognosis and long-term surveillance in patients with testicular cancer. by Dr Angela Cooper and Dr Seán Costelloe Incidence of testicular cancerTesticular cancer (TC) is […]
Use of serum free light chain analysis in screening for multiple myeloma in primary care patients
Identification of a serum or urine paraprotein is a key element in the diagnosis of multiple myeloma. Traditionally, this has been achieved using a combination of serum and urine electrophoresis, but this can result in incomplete investigation. The use of serum free light chains as an alternative screening test has been advocated to overcome this. […]
Pharmacogenomics in an acute myelogenous leukemia patient
This article examines the case of a patient who developed toxic levels of voriconazole while taking the antifungal prophylactically as part of her treatment regimen in addition to standard chemotherapy for a leukocyte neoplasm. The usefulness of molecular diagnostic testing as an aid in voriconazole dosing is discussed. by S. Rezaei, L. Collier and Dr […]
Diagnosis of diabetes mellitus
Diabetes is characterized by hyperglycemia, but diagnosis no longer depends exclusively on plasma glucose measurements. The endorsement of glycated hemoglobin as a diagnostic test for diabetes has seen its widespread adoption for this purpose: it is vital that its application in this role is appropriate and its limitations understood. by Dr Shirley Bowles IntroductionThe term […]