A diagnostic point-of care (POC) test would greatly improve case detection and management of pediatric tuberculosis (TB). Herein, we provide a brief overview of the challenges associated with diagnosing TB in children and recent evidence that points towards a future POC test based on transcriptomes in peripheral blood. by Dr S. Jenum, Dr J.E. Gjøen, […]
Molecular testing is increasingly recognized for guiding patient management and development of new targeted therapies. Meanwhile, there is an increased demand to perform testing on smaller volumes of tissue. Recent literature reports the use of ultrasensitive techniques to detect DNA mutations and translocations from stained cytology smears [1]. by Dr Laleh Hakima, Dr Maja H. […]
Type 1 diabetes is a multigenic disease in which the pancreatic β-cells are destroyed by an autoimmune process. At time of diagnosis, only poorly functional β-cell mass exists. Prediction of type 1 diabetes progression and prognosis using genetic markers may improve treatment strategies and increase the patient´s life quality. by Dr Caroline A. Brorsson and […]
Uromodulin kidney disease is a rare autosomal dominant kidney disease, characterized by hyperuricemia, gout and progressive kidney failure. Affected patients typically need renal replacement therapy in middle age. A considerable number of patients may reach end-stage kidney disease without a correct diagnosis, making improvements in diagnostic methods of vital importance. by Dr Tamehito Onoe and […]
A series of independent evaluations of the Beckman Coulter DxN VERIS Molecular Diagnostics System demonstrated how workflow efficiencies that can be achieved with the DxN VERIS have the potential to improve productivity, while making the best use of existing space and staffing levels. Background Virology laboratories throughout the world face a number of challenges that […]
Urinalysis may provide evidence of significant renal disease in asymptomatic patients. The microscopic urinalysis is vital to making diagnoses in many asymptomatic cases, including urinary tract infection, urinary tract tumours, occult glomerulonephritis, and interstitial nephritis.Presence or absence of different particles in urine sediment is crucial for clinical decision making. Urine sediment cells or particles provide […]
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