Author Archive for: 3wmedia

Sweat chloride is the gold standard diagnostic test for cystic fibrosis (CF) offering direct measurement of cystic fibrosis transmembrane conductance regulator (CFTR) protein function. Current methods are labour-intensive, complex, time-consuming and require relatively large sample volumes. Inductively coupled plasma mass spectrometry (ICP-MS) is an emerging technology capable of providing rapid and accurate sweat chloride concentrations […]

Liquid chromatography-mass spectrometry (LC-MS/MS) is an analytical chemistry technique that combines the physio-chemical separation capabilities of liquid chromatography (via conventional chromatography within a column) with the analytic power of mass spectrometry. It allows the user to properly ascertain the individual mass/charge ratio of analytes present in a chromatographic peak. The high throughput capabilities of this […]