A thorough understanding of the immune response to SARS-CoV-2 is necessary for the evaluation of the efficacy of vaccines and vaccine candidates against this virus. This article discusses how some parts of the humoral and cellular immune responses can be analysed to improve our understanding of how the body reacts to this virus.
Bruker Corporation has launched two new timsTOF instruments – the timsTOF SCP for unbiased single cell 4D-proteomics and the next-gen timsTOF Pro 2 with unprecedented proteomic depth. The instruments enable new applications and methods in unbiased proteomics, epiproteomics/PTM characterization, and unbiased, deep multiomic biomarker discovery, such as in cancer liquid biopsy research.
Flow cytometry is one of many analytical techniques used in clinical development to help discover new biomarkers and aid in development of new therapies. This article highlights how automated gating can expedite data processing and management, leading to improved productivity and insights in flow cytometry analysis for clinical research.
Optical fibres have revolutionized clinical practice in the form of the optical endoscope, and are now providing the framework for an entirely new endoscopic paradigm: all-optical ultrasound. Here we describe a phonon probe, which offers a route towards cellular resolution acoustic imaging – while also offering new capabilities such as label-free contrast and parallel spectroscopy […]
Although we have a reasonable understanding of a number of mechanisms of epigenetic regulation, we are still have a lot more to learn about the impact and influence of epigenetic regulation, particularly in relation to disease. CLI caught up with Professor Michael Skinner (Center for Reproductive Biology, Washington State University, USA) to find out more […]
Porvair Sciences has further expanded its range of high-performance microplate products for SARS-CoV-2 nucleic acid purification. The new KF deep well plate and tip comb plate combo are specifically designed to enhance the performance and productivity of the market-leading Thermo Scientific KingFisher range of nucleic acid purification systems. Krzysztof Kielmann, microplates product manager at Porvair […]
BBI Solutions has launched a new Jo-1 human chimeric antibody for use as a calibrator or positive control in assays to diagnose conditions such as connective tissue disease (CTD). BBI has used cell culture technologies in response to the concerning situation, as hospital visits continue to be dominated by Covid-related cases, leading to a drop […]
Nonacus, a provider of genetic testing products for precision medicine and liquid biopsy, and the University of Birmingham have partnered to develop a non-invasive urine test for bladder cancer. The test, which is expected to be available by mid-2022, will use highly sensitive liquid biopsy technology developed by Nonacus, and a panel of biomarkers validated […]
Thermo Fisher Scientific and Advanced Electrophoresis Solutions (AES), specialists in protein imaging technologies, have agreed to combine essential protein separation techniques with mass spectrometry (MS) to advance therapeutic protein development through streamlined characterization. Together, the companies will promote Thermo Fisher’s expertise as a leading provider of mass spectrometry technology for biopharma and proteomics applications, and AES’ ability […]
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