Prime Plus provides the most clinical value of any blood gas/critical care analyzer profile by adding essential tests for electrolyte balance (iMg), plasma volume (ePV), and kidney function (Urea, Creatinine, eGFR).
Ionized Magnesium (iMg)
Hypomagnesemia is a frequent finding in critically ill patients.1 Magnesium therapy guided by real
time ionized magnesium monitoring has been shown to improve outcome in these patients.2
Estimated Plasma Volume (ePV)
The plasma volume status of a patient is one of the top priorities in evaluating and treating critical illness including CHF, ARDS, AKI, Surgery, and Sepsis.3-5
Urea, Creatinine and eGFR
Over 50% of patients admitted to the ICU develop some degree of acute kidney injury.6 Creatinine, eGFR, and Urea monitoring provides early indication of changes in kidney function and helps guide therapy toprevent AKI.
pH PCO2 PO2 SO2% Hct Hb iMg Na K Cl TCO2 iCa
ePV GLU Lac Urea Creat/eGFR CO-Ox MCHC tBil HbF
1. Soliman HM. Development of ionized hypomagnesemia is associated with higher mortality rates.
Crit Care Med 2003;31(4):1082-7.
2. Wilkes NJ et al. Correction of ionized plasma magnesium during cardiopulmonary bypass reduces
the risk of postoperative cardiac arrhythmia. Anesth and Analg 2002;95(4) 828-834.
3. Kobayashi M et al. Prognostic Value of Estimated Plasma Volume in Heart Failure in Three Cohort
Studies; Clin Res Cardiol 2019;108(5): 549-561.
4. Niedermeyer, et al. Calculated Plasma Volume Status Is Associated With Mortality in Acute
Respiratory Distress Syndrome. Critical Care Explorations: September 2021, V3(9):1-9.
5. Kim HK et al. Prognostic Value of Estimated Plasma Volume Status in Patients with Sepsis.
J Korea Med Sci 2020;9(37):1-10.
6. Mandelbaum T et al. Outcome of critically ill patients with acute kidney injury using the AKIN
criteria. Crit Care Med 2011;39(12):2659-2664.