Even though IBS-D and BAD occur worldwide, the gold standard diagnosis method (75SeHCAT test) is not licensed in some countries and not common in standard clinical laboratories. The time span for this test is seven days, which is inconveniently time-consuming. Moreover, patients undergoing this test have to ingest a radioactive substance, which is another disadvantage of this method. Alternative methods, such as LC-MS or GC-MS, are technically complex.
Total bile acids 21 FS is conveniently applicable on all clinical chemistry analyzers. The liquid-stable, ready-to-use DiaSys reagent has a wide measuring range (up to 130 µmol/L), good precision and long onboard and calibration stability. It shows good reproducibility and minimum interference from endogenous substances that may interfere.