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Archive for category: Autoimmunity & Allergy

Autoimmunity & Allergy

Fig1 skin antigens

Anti-laminin β4 – a new autoantibody marker in pemphigoid disease

, 8 November 2025/in Autoimmunity & Allergy, Featured Articles /by panglobal

Laminin β4 (lamβ4) has been identified as a novel target antigen in anti-p200 pemphigoid, a rare autoimmune disease manifesting with subepidermal blisters. Anti-lamβ4 antibodies bind to the region of the dermal–epidermal junction and demonstrate pathogenic effects. A recombinant-cell indirect immunofluorescence assay has been developed for specific detection of anti-lamβ4 antibodies.

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https://clinlabint.com/wp-content/uploads/sites/2/2025/11/Fig1-skin-antigens.jpg 960 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2025-11-08 14:53:142025-11-06 15:19:04Anti-laminin β4 – a new autoantibody marker in pemphigoid disease
Infographic

Novel customizable immunoassay platform promises rapid, sensitive disease detection without complex laboratory requirements

, 8 November 2024/in Autoimmunity & Allergy, Featured Articles /by panglobal

A groundbreaking customizable immunoassay system developed by Japanese researchers offers rapid detection of disease biomarkers, allergens and other biomolecules with exceptional sensitivity, potentially revolutionising point-of-care diagnostics

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https://clinlabint.com/wp-content/uploads/sites/2/2024/11/Infographic.jpg 1920 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2024-11-08 11:12:272024-11-08 11:15:04Novel customizable immunoassay platform promises rapid, sensitive disease detection without complex laboratory requirements
AdobeStock 289688298

Hoxb8 MAT improves diagnosis of peanut allergy

, 7 November 2024/in Featured Articles, Autoimmunity & Allergy /by panglobal

A recent report published by the Food Standards Agency in the UK [Patterns and prevalence of adult food allergy (PAFA); https://shorturl.at/jnaLY] estimates that around 6% of the UK adult population have a clinically confirmed IgE-mediated food allergy.

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https://clinlabint.com/wp-content/uploads/sites/2/2024/11/AdobeStock_289688298.jpeg 1280 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2024-11-07 10:14:292024-11-07 10:14:29Hoxb8 MAT improves diagnosis of peanut allergy
AdobeStock 332129362

Weighted analysis of autoantibodies in new classification criteria for antiphospholipid syndrome

, 7 November 2024/in Featured Articles, Autoimmunity & Allergy /by panglobal

By Dr Jacqueline Gosink New American College of Rheumatology and European Alliance of Associations for Rheumatology classification criteria for antiphospholipid syndrome have been developed to aid cohort selection for research and clinical trials. The classification system includes both clinical and laboratory criteria, which are hierarchically clustered, weighted and risk-stratified to ensure high specificity.

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https://clinlabint.com/wp-content/uploads/sites/2/2024/11/AdobeStock_332129362.jpeg 1280 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2024-11-07 09:26:582024-11-07 10:05:21Weighted analysis of autoantibodies in new classification criteria for antiphospholipid syndrome
SciRhom

SciRhom raises €63 million to advance iRhom2-targeting therapies for autoimmune diseases

, 20 August 2024/in Autoimmunity & Allergy, E-News /by panglobal

Munich-based biopharmaceutical company SciRhom GmbH has secured a substantial €63 million (US$70 million) in Series A financing to accelerate the development of its pioneering iRhom2-targeting antibodies for autoimmune disorders. The oversubscribed funding round, co-led by Andera Partners, Kurma Partners, Hadean Ventures, MIG Capital, and Wellington Partners, will propel the company’s lead candidate toward clinical proof-of-concept […]

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https://clinlabint.com/wp-content/uploads/sites/2/2024/08/SciRhom.jpg 1280 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2024-08-20 08:47:442024-08-20 13:45:21SciRhom raises €63 million to advance iRhom2-targeting therapies for autoimmune diseases
Autoimmune Encephalitis Mosaic 6

Together at the pulse of neurobiology

, 20 August 2024/in Featured Articles, Autoimmunity & Allergy, Molecular Diagnostics, Rapid Tests & POC /by panglobal

A unique portfolio of neurobiomarker tests The testing landscape for neurological diseases has expanded rapidly in recent years due to the characterisation of many novel biomarkers. With over 15 years of experience in neurological analytics, EUROIMMUN offers an unparalleled portfolio of assays for determination of more than 80 neurobiomarkers in autoimmune diseases, neurological infections and […]

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https://clinlabint.com/wp-content/uploads/sites/2/2024/08/Autoimmune-Encephalitis-Mosaic-6.jpg 1034 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2024-08-20 08:32:562024-08-22 08:48:19Together at the pulse of neurobiology
EBO LOGO

Immunoblot with F-actin for autoimmune liver diseases

, 23 May 2023/in Autoimmunity & Allergy, E-News /by panglobal

The EUROLINE portfolio for autoimmune liver diseases (AILD) has been extended with the antigen F-actin and now features the DL 1300-9G with 10 antigens for the determination of AILD-related autoantibodies.

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https://clinlabint.com/wp-content/uploads/sites/2/2023/05/EBO_LOGO.jpg 1419 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-05-23 11:36:322023-11-29 15:54:08Immunoblot with F-actin for autoimmune liver diseases
Euroimmun Myositisblots

EUROIMMUN introduces comprehensive autoantibody test for myositis

, 28 September 2022/in Product News, Autoimmunity & Allergy /by panglobal

The EUROLINE Autoimmune Inflammatory Myopathies Profile has been expanded and now includes 20 antigens for detection and differentiation of autoantibodies that occur in idiopathic inflammatory myopathies (IIM).

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https://clinlabint.com/wp-content/uploads/sites/2/2022/09/Euroimmun_Myositisblots-e1664378806925.jpg 726 1000 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2022-09-28 14:06:182023-10-05 10:30:16EUROIMMUN introduces comprehensive autoantibody test for myositis
EUROLabPolaris klein

New automation technologies at the vanguard of IFA diagnostics

, 31 August 2022/in Featured Articles, Autoimmunity & Allergy /by panglobal

EUROIMMUN has been creating innovative solutions for immunofluorescence diagnostics for over thirty years. Continuing this long tradition, the company has over the last year introduced further groundbreaking products to increase the efficiency and standardization of indirect immunofluorescence assay (IFA) analyses. CLI talked to Dr Panagiotis Grypiotis, Head of Product Management Autoimmune Diagnostics, Endocrinology/Biologics and Automation […]

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https://clinlabint.com/wp-content/uploads/sites/2/2022/08/EUROLabPolaris_klein.jpg 665 1182 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2022-08-31 10:24:322023-11-29 15:53:14New automation technologies at the vanguard of IFA diagnostics
C50 Figure 1

ANCA-IIF: Still the screening method of choice

, 26 August 2020/in Featured Articles, Autoimmunity & Allergy /by 3wmedia

by Dr Petraki Munujos Systemic vasculitides are a group of inflammatory idiopathic clinical syndromes usually classified by the size of the vessels being affected. Among them, the small vessels vasculitides show clear associations with the presence in the patients sera of antibodies directed against cytoplasmic antigens of neutrophils (ANCA).

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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C50_Figure-1.jpg 136 300 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:46:522024-08-26 10:23:18ANCA-IIF: Still the screening method of choice
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