Bio-Rad Laboratories has introduced three StarBright Dyes designed for use with a 355 nanometer UV laser in flow cytometry applications. StarBright UltraViolet 510, 665, and 795 Dyes offer exceptional brightness with narrow excitation and emission profiles for precise resolution, expanding Bio-Rad’s range to provide greater flexibility in multicolour flow cytometry panels.
Bio-Rad’s line of StarBright Dyes offers researchers unique fluorescent nanoparticles conjugated to highly validated flow antibodies, which are compatible with most experimental protocols and flow cytometers, including Bio-Rad’s ZE5 Cell Analyzer and S3e Cell Sorter. The dyes are resistant to photobleaching and are highly stable with no loss of signal in fixation, and minimal lot-to-lot variation helps to ensure consistent staining and deliver reliable results.
“We are proud to add three new dyes to Bio-Rad’s StarBright UltraViolet portfolio, following its launch last year, and are now better positioned to support researchers with their flow cytometry workflows by providing a range of high-performance dyes excitable by the 355 nanometer UV laser to existing alternatives,” said Mike Blundell, PhD, Bio-Rad Product Manager, Flow Cytometry, Life Science Group. “The unrivalled brightness of the dyes enables enhanced resolution of low-density antigens and rare populations while maintaining consistent and reproducible staining without the need for special buffers.”
Codexis and seqWell announce partnership to accelerate commercialization of seqWell’s genomics workflow solutions
, /in E-News /by panglobalCodexis and seqWell have announced the initiation of a strategic partnership and investment to accelerate the commercialization of seqWell’s genomics workflow solutions. Codexis, a leading enzyme engineering company enabling the promise of synthetic biology, and seqWell, a developer of transformative library preparation products for demanding genomics applications, plan to collaborate on using Codexis’ CodeEvolver platform […]
Biotium acquires CAT5 FFPE RNA/DNA extraction technology from Cell Data Sciences
, /in E-News /by panglobalBiotium, a supplier of cutting-edge life science reagents, has acquired Cell Data Sciences RNAstorm and DNAstorm kits for RNA/DNA extraction. Biotium, which previously distributed the Cell Data Sciences kits, will now be their sole manufacturer. The extraction kits will be offered from the Biotium website and authorized distributors.
Arctoris and Evariste Technologies form a joint venture to identify novel small molecule cMET Inhibitors for Non-Small Cell Lung Cancer
, /in E-News /by panglobalArctoris, a tech-enabled biopharma company, and Evariste Technologies, an AI-drug discovery company, have formed a joint venture to identify novel small molecule kinase inhibitors for treatment of patients with Non-Small Cell Lung Cancer (NSCLC).
Insight into the importance of controls in molecular diagnostics assays
, /in Featured Articles /by panglobalControls are a crucial part of any assay. Without them, our work is, at best, simply a waste of time and reagents. We know we need them but we probably should give them much more thought than we do. CLI caught up with Dr John Hedges, Director of Research and Development at Asuragen (a Bio-Techne […]
PCR allows rapid, differentiated dermatomycosis diagnostics
, /in Featured Articles /by panglobalThe diagnosis of fungal infections of the skin and nails has undergone a paradigm shift in recent years. Traditional culturing methods have in many cases been replaced by PCR-based diagnostics, which provide greater accuracy and yield results ina fraction of the time. The fast, differentiated detection of dermatomycosis pathogens enables prompt targeted treatment of infections.
Molecular subtypes of metastatic urothelial carcinoma and treatment options
, /in Featured Articles /by panglobalUrothelial carcinoma is a common cancer and patients with metastatic urothelial cancer (mUC) have very poor outcomes. Many mUC patients do not have durable responses to systemic treatment and are exposed to toxic side effects that negatively impact the patient’s quality of life. Identifying novel biomarkers for therapy and selecting the best treatment option for […]
Two common peak-integration protocols for the quantification of M-proteins in serum protein electrophoresis
, /in Featured Articles /by panglobalQuantification of M-proteins plays an important role in diagnosing and managing patients with monoclonal gammopathies. This is traditionally performed by integrating abnormal monoclonal peaks in the electrophoretogram, using either a perpendicular drop (PD) or tangential skim (TS) method. In this article, we describe the advantages and disadvantages of the PD and TS integration methods and […]
Exploring blood biomarkers for monitoring COVID-19 disease progression and outcomes and impact of SARS-CoV-2 variants of concern
, /in Featured Articles /by panglobalIn April 2020, the Royal College of Pathologists published recommendations for a set of blood COVID-19 biomarkers to monitor disease severity and progression, which have since been employed by many UK hospital diagnostics services. Subsequent findings regarding biomarkers and their ability to distinguish or predict severe disease remain under investigation and emerging evidence highlights that […]
Bio-Rad introduces 3 new StarBright UltraViolet dyes to enhance multiplex flow cytometry
, /in Product News /by panglobalBio-Rad Laboratories has introduced three StarBright Dyes designed for use with a 355 nanometer UV laser in flow cytometry applications. StarBright UltraViolet 510, 665, and 795 Dyes offer exceptional brightness with narrow excitation and emission profiles for precise resolution, expanding Bio-Rad’s range to provide greater flexibility in multicolour flow cytometry panels.
Bio-Rad’s line of StarBright Dyes offers researchers unique fluorescent nanoparticles conjugated to highly validated flow antibodies, which are compatible with most experimental protocols and flow cytometers, including Bio-Rad’s ZE5 Cell Analyzer and S3e Cell Sorter. The dyes are resistant to photobleaching and are highly stable with no loss of signal in fixation, and minimal lot-to-lot variation helps to ensure consistent staining and deliver reliable results.
“We are proud to add three new dyes to Bio-Rad’s StarBright UltraViolet portfolio, following its launch last year, and are now better positioned to support researchers with their flow cytometry workflows by providing a range of high-performance dyes excitable by the 355 nanometer UV laser to existing alternatives,” said Mike Blundell, PhD, Bio-Rad Product Manager, Flow Cytometry, Life Science Group. “The unrivalled brightness of the dyes enables enhanced resolution of low-density antigens and rare populations while maintaining consistent and reproducible staining without the need for special buffers.”
Thermo Scientific to connect its Cascadion SM Clinical Analyzer to Inpeco’s Flex Lab laboratory automation system
automation, laboratory automation system, /in Product News, E-News /by panglobalThermo Fisher Scientific and Inpeco have agreed to develop connectivity between the Thermo Scientific Cascadion SM Clinical Analyzer and the Inpeco FlexLab laboratory automation system (LAS). This interface will enable primary tubes on the Inpeco LAS to be transported to the Cascadion analyzer for automated loading, pre-treatment, and analysis.