C254 AniBiotech

Rapid diagnostic tests for pneumonia

The Biocard Mycoplasma pneumoniae IgM and Chlamydia pneumoniae IgM tests are lateral flow cassette tests for rapid detection of pneumoniae IgM antibodies in fingertip wholeblood samples, as well as in serum and plasma samples. The tests are CE-marked, easy and quick to perform: the results are available in 5–10 minutes. Most diagnosis of C. pneumoniae is done serologically and modified microimmuno-fluorescence methods are commonly used. Other test procedures, such as enzyme immunoassays and PCR methods, are also used, but all of these methods require trained personnel and a skilled interpreter, whereas a positive Biocard test result is a simple and rapid aid for the diagnosis of acute C. pneumoniae and M. pneumoniae infection. A typical test pack contains: 20 aluminium pouches containing a test cassette, 20 automatic lancets for obtaining a blood sample, 1 plastic vessel containing 20 pieces of 10 μl glass capillary, 20 tubes containing 0.5 ml of sample dilution buff er, 20 alcohol swabs, and an instruction leaflet.
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Randox logo

Liquid urine chemistry control

Designed to be both easy and convenient for laboratory staff to use, the Acusera liquid urine control includes fully assayed target values for 18 commonly performed urine chemistry tests including microalbumin and hCG enabling consolidation and ultimately cost savings. Th e stable liquid format of the control eliminates the need for reconstitution and thus reduces the amount of human handling and the subsequent risk of pipetting errors. The material is manufactured from 100% human urine providing not only a matrix similar to the patient sample but also reducing antibody interference and the possibility of control values shift ing aft er a change of reagent batch. A 10ml vial size and an open vial stability of 30 days at +2–8oC for all parameters ensures both waste and, most importantly, costs are kept to a minimum. As a true third party, control laboratories can expect an unbiased, independent assessment of analytical performance. Instrument-specific target values and ranges are also provided for many common brands of clinical chemistry analysers. The liquid urine control is compatible for use with Acusera 24.7, Randox’s new web-based inter-laboratory data management programme. With an extensive range of data management tools, users gain access to worldwide peer group data that is updated every 24 hours, providing the most up-to-date-information available.
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C248 Genalyte

One-step screening for common connective tissue disease autoantibodies

Created to simultaneously screen for several of the most common autoantibodies found in autoimmune connective tissue disorders, such as systemic lupus erythematosus (SLE), the Maverick ENA 4 and ENA 6 assay kits are the first available for the Maverick Detection System. Their simplified one-step workflow delivers accurate results in 15 minutes and can be run using very small volume samples from a variety of matrices, including serum and plasma. The ENA 4 assay tests for the presence of four of the most commonly measured extractable nuclear antigens (ENA), including SS-A, SS-B, Sm and RNP, while the ENA 6 assay includes two additional commonly measured antigens–Scl-70 and Jo-1, so covering six multiplexed tests per sample. The assay results are highly reproducible, show excellent correlation to ELISA and are up to ten times more sensitive. The assays are available to participants in the company’s Early Access programme, which enables scientists to gain pre-launch access to multiplexed autoantibody assays and the Maverick Detection System. This uses a proprietary chip based on silicon photonics to simultaneously analyse multiple proteins from a single small sample. The multiplexing technology simultaneously screens for the detection of autoantibodies using a one-step process that eliminates the washes, incubations, reagents and processing steps typically associated with other technologies. Semi-quantitative results are reported for each analyte, eliminating the need for reflex testing. The assays are simple to use and rapid – results are available in only 15 minutes, including just two minutes of hands-on time. A number of higher plexed assays for autoimmune diseases, including rheumatoid arthritis, celiac disease and others, are also in development.
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C261 MPbiomedicals Multisure Option 07

Immunochromatographic assay for hepatitis C virus

It has been estimated that 3 to 4 million people are infected with hepatitis C virus (HCV) each year. Four out of five people develop chronic hepatitis C infection, which can subsequently lead to liver cirrhosis and/or liver cancer. Early detection is the key to combating hepatitis; hepatitis C infection can be effectively controlled or treated if it is diagnosed early. HCV ELISA and rapid tests are widely used for screening and diagnosis of hepatitis C infection. These tests use specific antigens from the structural region and non-structural regions of the virus to detect the presence of antibodies to HCV. Reactive samples from screening tests are then confirmed by immunoblot assay. The MULTISURE HCV Antibody Assay is a qualitative immunochromatographic assay, intended for the detection of antibodies specific to HCV core, NS3, NS4 and NS5 antigens. The test is based on the capture of HCV antibodies using immobilised HCV recombinant antigens on a nitrocellulose membrane and the subsequent detection of captured analyte using goat anti-human IgG conjugated to colloidal gold. It has been developed from the patented reverse-flow test platform, giving greater sensitivity and easy-to-read visual signals. Similar to a confirmatory immunoblot, this assay can detect and differentiate the structural and non-structural HCV proteins. The test result pattern may, therefore, offer information such as the possible phase of the Hepatitis C infection. This simple and rapid assay takes only 15 minutes and is easy to use. It is an instrument-free platform and does not require highly trained personnel to perform the test, thus making it suitable for use in a point-of-care setting. With shortened turnaround time, patients are diagnosed early and have wider access to treatment and care.

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KZ DocUReader 2

Performing urinalysis in the easiest and most efficient way

The new DocUReader 2 system is designed for physician’s offices and smaller laboratories to read and evaluate the LabStrip U11 Plus urine test strips with 50 samples / hour throughput.   The compact design of this lightweight instrument offers the broadest features and highest flexibility available on any desktop size urine analyzer. Auto start functionality and advanced, patented detection technique guarantee fast and accurate results. User friendly software ensures flexible testing and reporting options as well as effective data management. Manual entry of color and turbidity data improves clinical utility. Automated result and worklist transmission is enabled by LIS connectivity. More accurate data entry and reduced transcription errors can be achieved by optional barcode reader and external keyboard. Continuing the mission of the previous DocUReader, the new instrument features simple operation, cost efficiency, and high quality. The DocUReader 2 Pro additionally provides enhanced quality control and connectivity capabilities, operator management, and extended memory capacity.

More info – contact: sales@e77.hu
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C284 Astra

High quality diagnostics for personalized medicine

Extending the company’s range of diagnostic testing solutions, the kits enable DNA extraction and the identification of polymorphisms in genes linked to disease or drug metabolism. The kits are real time PCR-based, and validated on multiple PCR instruments from leading manufacturers. These include thrombosis kits for the detection of polymorphisms in F5 and F2 genes, supporting disease management. The drug sensitivity kits determine an individual’s susceptibility to indirect anticoagulants and other drugs, including polymorphisms in CYP2C9, VKORC1, CYP2C19 genes. This knowledge is important in correct dosage prescription, which can vary hugely across genotypes. The Multi DNA extraction kit provides fast, easy extraction from various sample types, including serum, plasma, dry blood spots, urine, saliva and epithelial cells.
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Random access benchtop analyser

The RX daytona plus provides high quality testing on a compact, easy to use clinical chemistry analyser with accurate results. A fully automated, random access, benchtop analyser, it features a throughput of 450 tests per hour including ISE. Its comprehensive and flexible test menu allows the consolidation of a wide range of routine and specialized tests including routine chemistries, specific proteins, therapeutic drugs and drugs of abuse. Dedicated RX support teams provide technical support as needed, maximizing laboratory efficiency.
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C263 DiaSource

1,25 (OH)2 Vitamin D ELISA

The hormone 1,25 dihydroxy vitamin D is formed in the kidney and has important functions in calcium metabolism; hence impaired kidney function can result in a decrease in 1,25 dihydroxy vitamin D levels and the development of renal osteopathy, which is characterized by osteomalacia and osteitis fibrosa. This company’s assay development programme is focusing specifically on new vitamin D assays. After the recent launch of the 25-Hydroxyvitamin D Total RIA and ELISA assays based on patented monoclonal antibodies manufactured in-house, a new easy-to-use 1,25 dihydroxy Vitamin D ELISA is launched. This ELISA is specifically designed to be used manually as well as on open automated systems. As the total assay time is less than 6 hours, the patient’s results will be available the same day. The assay has been validated on the Stratec GEMINI open ELISA automated analyser (Stratec Biomedical GMBH – Germany) and a validated protocol will be made available to all Stratec GEMINI users.
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C279 SFRI

Blood cell counter for small labs

This compact 30 test/hour analyser is designed for daily use in labs with low throughput and offers all the qualities of a 60 test/hour instrument at an aff ordable cost. The COUNTENDER 30 features 20 parameters, 3 histograms and excellent CVs. It outclasses most 60 tests/hour analysers in terms of performance and quality of results and is top of its category, providing results in under 2mins. It also features very low reagent consumption. Combining simplified maintenance and long shelf-life of the company’s reagents (up to 36 months), the blood cell counter has low servicing requirements and enables signifi cant cost per test reduction for labs.
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C267 BioSystems

Reagent for CO2 measurement

Analysis of CO2 is performed as part of an electrolytic analysis in the investigation of acid-base disorders, monitoring kidney disease (bicarbonate absorption function) or hypertension. In the body, 95% of CO2 is present as HCO3- (bicarbonate). Elevated or low levels of HCO3-may indicate a variety of disorders. The Carbon Dioxide Reagent is available in diff erent presentations, as well as Dioxide Standard and Carbon Dioxide Control.
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