C132 Euroimmun 01

Immunofluorescence microscope and software system

The new EUROPattern system provides automated high-speed acquisition, archiving and interpretation of immunofluorescence images, supporting autoimmune disease diagnostics, in particular the analysis of anti-nuclear antibodies (ANA) and anti-neutrophil cytoplasm antibodies (ANCA). Alongside a high-precision optical system it has a controlled LED, which maintains a constant light flux, ensuring highly reproducible results. The exceptionally long life span (over 50,000 hours) and low power consumption of the cLED ensure cost-effectiveness. The microscope can process up to 500 analyses in succession, correctly identifying the slides by means of matrix codes. The EUROPattern system includes powerful pattern recognition software which identifies and classifies all ANA, anticytoplasmic antibodies and ANCA, even if more than one antibody is present. The system also evaluates anti-dsDNA antibodies on Crithidia luciliae as well as transfected cell substrates. Results are viewed on the PC screen, and can be checked retrospectively at the microscope if necessary. Images from further substrates such as liver, kidney and stomach can be recorded and archived. The laboratory management system EUROLabOffice, organises workflow and documents all data and processes. The software consolidates all results into one report per patient and also compares new findings with previous records. Different user levels provide a hierarchical review of results, thus increasing security. Final reports can be signed electronically and forwarded at a click of the mouse.
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C135 Sobioda 01

Anaerobic, microaerophilic, capnophilic environment system

SOBIODA introduces its new system BACTR Plus for the automated and standardized creation of specific environments for fastidious bacteria. The BACTR Plus operates with the substitution principle: it evacuates air from the jar with the vacuum pump and replaces it with the specific gas mixture in relation with the cultivated bacteria. The system replaces all chemical bags (for anaerobiosis, micro-aerophily, CO2 supplementation). It is a very economical and fast alternative to chemical bags and chambers. To ensure traceability of any use of the system, the BACT-R Plus is able to save on the SD card all data related to the user, the jar, the gas, the programme. The reproducibility of the atmosphere creation contributes to the standardization of the procedure, allowing IOS15189 requirements to be achieved.
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C138 Ark oxcarbazepine 1 01

Oxcarbazepine metabolite (MHD) assay

Oxcarbazepine is a pro-drug indicated for treatment of partial seizures, a form of epilepsy. Serum concentrations (3-35 mg/L) of the active monohydroxy derivative (MHD) metabolite are associated with clinically effective control of partial seizures. Toxic side effects may occur more commonly at concentrations greater than 35 mg/L. Therapeutic drug monitoring (TDM) is justified when changes are expected that might alter MHD clearance including pregnancy, concomitant use of liver enzyme inducing drugs, or renal insufficiency. The ARK Oxcarbazepine Metabolite Assay is a homogeneous enzyme immunoassay intended for the quantitative determination of MHD in human serum on automated clinical chemistry analysers. The ARK Oxcarbazepine Metabolite Assay is available for export outside the US. It has not received clearance/approval by the U.S. FDA.
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C114 Greiner image1 01

Rapid detection of toxigenic C. difficile

The Genspeed C.diff OneStep test identifies toxigenic C. difficile by combining detection of Glutamate Dehydrogenase (GDH), Toxin A, Toxin B and binary toxin in a single, molecular diagnostic test. The complete analysis including the detection on the Genspeed R2 analyser takes under 100 min. The new test addresses one of the most serious threats to healthcare systems worldwide, Clostridium difficile infection (CDI), which is believed to be the most common healthcareassociated infection. The disease is causing antibiotic-associated diarrhea (AAD) that may lead to pseudomembranous colitis and even to death. In a 2013 pub-lished report, the Center for Disease Control (CDC) in the USA categorized C. difficile infections as “Threat Level Urgent”, the highest level available. The Genspeed C.diff OneStep test features a simple, one-step molecular diagnostic test, avoiding the currently used sequential 2-step diagnostic test procedures which combine different test systems and assay principles for GDH and the C. difficile toxins. The rapid test provides conclusive results without the need for confirmatory re-testing and enables inter-laboratory comparisons of test results. Ready-touse reagents and automated dispensing minimize the number of manual process steps within the workflow. The Genspeed R2 analyser represents a reliable solution for customers interested in fast and accurate results. The virtually service-free system is simple to operate and is available at an attractive cost-benefit ratio. Genspeed products are currently available for sale in the EU and EFTA countries only. Availability in other countries outside the US is on request.
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C139 Zivak 01

Fully automated 25-OH Vitamin D2/D3 LC-MS/MS analysis

An innovative combination provides the NIST (National Institute of Standards and Technology) tested LC-MS/MS Vitamin D2/D3 analysis kit with an accuracy of 96%, together with the Zivak fully automated sample preparation and injection system. This innovation now enables laboratories to receive accurate and fast LC-MS/MS Vitamin D2/D3 results in 1.7 minute per test, including sample preparation, sample injection and analysis run time. While preparation is in process, the Zivak Multitasker injects at the same time the already prepared samples into the LC-MS/MS instrument. This efficient process combined with the Zivak 25-OH Vitamin D2/D3 analysis kit where the analysis run time is about 1.5 minute now makes it possible to place the samples into the sample preparation tray and receive results in a fully automated way. The Zivak-Multitasker can handle up to 220 samples in one run.
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C149 Mast Group cropped 01

Diagnostic antisera for bacterial identification

MAST ASSURE Bacterial Agglutinating Antisera products are a comprehensive range of polyvalent and monovalent diagnostic antisera for bacterial identification. Bacterial serotype is easily determined according to the expression of flagella (H) and somatic (O) antigens.  Mast Antisera products are used globally for antigenic analysis of clinically significant bacteria, including MAST ASSURE Salmonella Antisera for identification of the species within the genus Salmonella using the Kauffmann-White Scheme for classification. The MAST ASSURE product range features simple slide and test tube agglutination methods and easy to read results. All antisera are derived from immunized rabbits, adsorbed to remove cross agglutinins and filter sterilized. Presented in 2ml dropper bottles, the reagents are user friendly and ensure minimal laboratory wastage. An extensive range of antisera is available from stock with a large range of sera manufactured to special order.
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C109 EDAN

POC immunoassay analyser

Multiple studies indicate a large number of diseases including cancer, infectious and cardiac diseases can be avoided, or even cured with early detection. The m16, a POCT magnetic immunoassay analyser with advanced magnetic bead-linked GMR (Giant Magneto Resistive) biosensor, can maximise and shorten the clinical laboratory’s turn around period, thereby providing faster, more accurate results and optimizing the clinical treatment’s efficiency.

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C078 Diagnostica Stago cropped

Automated hemostasis analyser

Designed for high volume laboratories, the STA R Max is an innovative and scalable analyser that can be adapted to any lab organization, whether or not it is connected to an automation track system. It brings productivity and reliability to laboratories for their routine and specialized hemostasis assays. The analyser offers the highest loading capacities to enhance walkaway capabilities: 215 samples, 70 reagent positions, 1000 cuvettes on board. True STAT management ensures fast turnaround time (TAT). Autoverification capabilities are built-in and a TAT report helps monitor performances. Ready to operate 24/7, the analyser does not require time to restart. A new hardware design enhances ergonomics while the intuitive user interface ensures seamless integration for laboratory staff . The extended traceability function meets quality requirements. Innovative services include accreditation support and remote diagnosis. The viscosity-based (mechanical) detection system enables immediate delivery of accurate and precise results. Advantages include insensitivity to any type of coloured plasma, maximum precision for weak clot detection and standardization between Stago systems. The environmentally friendly design provides savings because of the use of a limited and contained fluidic waste system and the reduction of disposable waste (1 cuvette = 1 test). All common tube sizes are accepted with automatic positioning of barcode. A wide range of dedicated reagents, quality controls and calibrators is available, offering maximum sensitivity and reproducibility for all tests.
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C131 Panasonic image1 01

Sample storage freezer

Panasonic’s Classic Eco MDF-DU300H with hydrocarbon (HC) refrigerants minimizes energy consumption while reducing environmental impact. The introduction of natural HC refrigerants to the latest 333L ULT freezer results in more efficient cooling due to their high latent heat of evaporation. With a power consumption of just 5.9 kWh/day – a 45% reduction compared to equivalent non-HC models – this could lead to potential savings of over €3,000 in energy costs over 10 years. As well as reducing running costs, the use of more efficient refrigerants results in improved performance with reduced pull down times for even greater sample security. Because of their exceptionally low global warming effect, HC refrigerants are also much better for the environment.
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C143 Siemens image1 01

POC analyser management system

Addressing the challenges faced by point-of-care (POC) coordinators in the laboratory, the Ecosystem is an integrated component of the RAPIDComm Data Management System, an informatics solution which centrally manages Siemens in vitro diagnostic analysers and operators. The system encompasses eight core components including device management, operator management, quality control, compliance reporting, competency management, inventory management, remote monitoring and mobile access. POC testing continues to grow at a rapid pace and there is a strong need to provide fast and reliable results in order to improve patient outcomes and optimize clinical workflow. Although solutions for each of the eight core components do exist individually, efficiently managing all aspects of a POC testing programme requires close collaboration among hospitals, device manufacturers and IT vendors. The Siemens POC Ecosystem helps to address this challenge by implementing an integrated solution which improves the efficiency and effectiveness of POC programmes. The Ecosystem solution manages secure access to POC devices, oversees quality control, manages staff training plus identifies and resolves issues from any location via the remote access facility. This helps to ensure the manageability of instruments and consumables for potentially hundreds of testing devices throughout a Trust. External compliance requirements are also met while reducing costs and improving efficiencies. Ecosystem takes the core needs of a POC programme into consideration with a focus on helping POC coordinators improve control, effectiveness and transparency. The Ecosystem solution allows POC data management from anywhere within a hospital using tablets and smart phone, which improves the ability of POC coordinators to quickly and efficiently resolve issues.
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