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November 2025
The leading international magazine for Clinical laboratory Equipment for everyone in the Vitro diagnostics
Prins Hendrikstraat 1
5611HH Eindhoven
The Netherlands
info@clinlabint.com
PanGlobal Media is not responsible for any error or omission that might occur in the electronic display of product or company data.
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Immunoturbidimetric Cystatin C assay
, /in Product News /by 3wmediaCystatin C (CysC) is an endogenously expressed, non-glycosylated protein known as a sensitive biomarker for early detection of kidney failure. Beside its obvious advantages over creatinine in estimating the glomerular filtration rate, it has not yet found its way in clinical routine. One major reason for this was the lack of a suitable standardization process, which changed in 2010 with the availability of the certified reference material, ERM-DA471/IFCC. DiaSys achieved excellent results in a recent multicentre study with its Cystatin C FS assay with major advantages over competitors. The results showed that among all tested immunoturbidimetric CysC assays, only the DiaSys test met the performance criteria at the four relevant concentrations. Cystatin C FS is a particle-enhanced immunoturbidimetric test featuring outstanding analytical sensitivity, high prozone security and excellent onboard/calibration stability.
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Mobile connection POC hemoglobin analyser
, /in Product News /by 3wmediaPOC Connect is the world’s first mobile data management solution designed for a reagent-free hemoglobin testing device. The simple android application enables the user to store, access and transmit hemoglobin results directly from a DiaSpect Tm hemoglobin analyser to a smartphone via Bluetooth. It is now possible to link Hb results with customizable unique IDs, QC information, Cuvette LOT numbers and dates and times, as well as transfer data easily via a file download or through email so it can be added to a central database or lab information system (LIS). The DiaSpect Tm device can be purchased with integrated Bluetooth, meaning there is no need to purchase an additional external Bluetooth dongle. This new solution will prove useful in countries with challenging environmental and geographical conditions where remote hemoglobin testing and access to internet can often be difficult.
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200 test/h benchtop analyser
, /in Product News /by 3wmediaBioSystems is introducing BA200, a benchtop analyser with a real throughput of 200 t/h with any combination of methods and parameters (or up to 286 t/h including 4-channel ISE option), washing station, barcode identification and ISE capabilities. Offering the highest loading capacity of its segment, with 88 positions barcoded, that could be adjusted with specific adaptors to be used either as reagent, sample (primary or pediatric tubes), standard or control, it provides maximum configuration flexibility to adapt to the workload of any small or medium size laboratory, from routine to special chemistries. A BioSystems’ patented LED light source allows a precise focus in the reading spot area with no energy loss, increased signal and a sustained performance over its lifetime, over 50,000 hours of continuous operation without change of intensity, reducing their maintenance to almost zero. Also, the newly developed Dynamic Baseline procedure allows multiple readings to be made as the rotor is spinning to obtain highly accurate blank readings used to offer higher reliability for low absorbance values, thus improving significantly the CV% of the test at low values. Finally, the BA200 system introduces also a dedicated range of reagents in package size adequate to small and medium laboratories (but also fully compatible with BA400 system), ensuring the highest performance and on-board stability.
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Sample collection processing system
, /in Product News /by 3wmediaAlmost 70% of clinical labs process mistakes happen during the sample collection phase, a crucial step for the entire diagnostic process. Today ProTube ensures unparalled reliability and complete biologic sample traceability, along the entire blood sampling phase. Starting from the positive patient identification to correct tube selection and labelling automation, ProTube tracks the whole sample process, through advanced data analytics systems and LIS real-time communication. Correct patient identification, no tube mismatches, process automation and 100% traceability are the key steps that lead to an improvement in the clinical lab workflow; ProTube allows the operator to save time in checks and manual operations, thus enabling the management of 40% more patients per hour (if compared to a centralized labelling system, see Plebani paper on “Pre-analytical phase” in Clinical Chimica Acta, 2015).
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MicroRNA enzyme immunoassay
, /in Product News /by 3wmediaBioVendor has now launched hsa-miR-21-5p miREIA, a quantitative assay combining molecular diagnostics and immunoassay technology. MiRNA isolated from a patient sample is hybridized to a complementary biotinylated DNA oligonucleotide probe. The miRNA/DNA hybrids are then processed in an ELISA format in a microtitre plate coated with a monoclonal antibody specific to perfectly matched miRNA/DNA dimers. The miREIA kits have been designed to quantify circulating miRNA from whole blood, enabling investigators to explore these promising biomarkers in various conditions including cancer, cardiovascular diseases, pulmonary diseases, regulation of immunological processes, reliably and in an easy-to-use format.
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Uromodulin ELISA for kidney function diagnostics
, /in Product News /by 3wmediaA new CE-labelled Uromodulin ELISA allows measurement of the uromodulin concentration in serum or plasma, and represents a sensitive test for kidney function loss. Uromodulin is a glycoprotein which is synthesized exclusively in the kidneys and subsequently secreted. When renal function is impaired, the uromodulin concentration in the serum sinks rapidly. Thus, renal disorders can be detected at a very early stage, even when there are few symptoms. Uromodulin determination supplements established kidney function markers such as creatinine. Moreover, it enables detection of renal insufficiency in the creatinine-blind area in the initial stages of kidney disease. Uromodulin measurement is also suitable for monitoring kidney vitality during therapy, predicting clinical outcome after kidney transplantation and enhancing risk prediction for cardiovascular diseases. In the ELISA, uromodulin is detected using microplates coated with anti-uromodulin antibodies. The uromodulin concentrations are established using a simple cut-off-based interpretation (normal value in health adults around 200 ng/ml). External factors such as body weight, nutrition or muscle mass do not need to be factored into the results by additional calculations, as with classic markers. The fast and simple test procedure takes less than 3 hours and is fully automatable on all open ELISA processers.
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Hematology systems
, /in Product News /by 3wmediaThe Alinity h-series of systems integrates hematology workflow, from high- throughput Complete Blood Count (CBC) analysis to automated slide making and staining. With a bi-directional, internal conveyor and a throughput of 125 CBCs per m2, it delivers high performance in one of the most compact footprints available. The system is composed of two Alinity hq modules and an Alinity hs module in a hq-hs-hq configuration. The Alinity hq analyser delivers a CBC with an expanded 6-part White Blood Cell (WBC) differential that includes routine and several advanced parameters using Advanced MAPSS (Multi Angle Polarized Scatter Separation) technology. With the Alinity hs slide maker/stainer and the integrated robotic sample management, the Alinity h-series of systems delivers unprecedented uniformity, flexibility, operational productivity and confidence to the lab. The systems are not commercially available in all countries, including the USA.
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Laboratories across Europe evaluate and adopt the Atellica Solution from Siemens Healthineers
, /in Product News /by 3wmediaLBM Bioesterel in France, Arcispedale S. Maria Nuova in Italy and Friarage Hospital in the United Kingdom are among the first laboratories to install the Atellica® Solution immunoassay and clinical chemistry analysers. The trending motivators for installing the latest innovation from Siemens Healthineers include the unprecedented flexibility to automate redundant and complex procedures to simplify testing workflows and to grow patient testing capacity. This is expected to enable the laboratories to keep up with rising demands and decreasing reimbursement rates—all in an effort to achieve long-term sustainability in a value-based healthcare delivery model.
www.healthcare.siemens.com/integrated-chemistry/systems/atellica-solution-analyzers“Our company is facing a significant reduction in margins due to lower social security payments,” explained Dr. Pierre-Antoine Flé, Associate Director at LBM Bioesterel in France. “In order to limit this impact while increasing our production capacity, our company has chosen the Atellica Solution, which responds particularly to our future needs.”
With the flexibility to combine up to 10 components into more than 300 customizable configurations, to operate either as a standalone system or connected to Aptio® Automation and to integrate seamlessly with other disciplines in a total laboratory system, the Atellica Solution offers scalability for long-term growth.
LBM Bioesterel anticipates it will be able to redeploy up to 30 percent of its staff. This is because of the ability to manage the configuration with a single operator and because of features such as automatic quality control (QC) and calibration with on-board refrigeration in the Atellica® Sample Handler—an integrated component of the Atellica Solution. Laboratories can program the Atellica Solution to automatically deploy the right materials at the right time to specific analysers to perform QC and calibration without operator intervention. This function significantly streamlines otherwise complex procedural workflows and lessens hands-on time for the operator, while eliminating unnecessary waste and decreasing the potential for human error.
Friarage Hospital in the United Kingdom, a member of the South Tees Hospitals NHS Foundation Trust, was drawn to automatic QC and calibration and to other proactive features designed to increase efficiency in the lab.
“We are very pleased with the support from the Siemens Healthineers teams both in setting up the new instrumentation and in the handling of verification, validation and global study protocols,” said Karl Hubbert, Services Manager Pathology, at Friarage Hospital. “We are looking forward to reduced maintenance and intervention elements, on-board QC stability and programming of QC intervals, as well as sorting of samples post analytics.”
Designed with algorithms to monitor system operations, the Atellica Solution can automatically initiate alerts and recommendations for corrective actions to maximize workflow. A system check and recovery procedure is included in the daily maintenance and also available on demand. This feature increases productivity, minimizes downtime, reduces the need for sample reruns and optimizes consumables and reagent usage.
For Dr. Luigi Vecchia, Director of Clinical Chemistry and Endocrinology Laboratory at Arcispedale S. Maria Nuova in Italy, independent sample management and quality control are priorities.
“The Atellica Solution—with its advanced technical features from sample transportation to real prioritization of urgent samples, and from reagent management to calibration and quality control management—takes us to the future of the laboratory. We are proud to be among the first to test it,” said Dr. Vecchia.
The patented, bi-directional, magnetic sample-transport technology and multi-camera vision system for intelligent sample routing provide independent control over every sample, whether routine or STAT (emergency). The immunoassay analyser uses a dual incubation ring design, rigorous temperature and humidity controls of the reaction environment, powerful magnets for relevant particle separation and robust washing protocols to deliver high throughput, while contributing to rapid and high-precision results.
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Specific proteins tests for urine samples
, /in Product News /by 3wmediaUrine testing provides unique information pertaining to a multiple series of renal and extra-renal diseases.
Based on immunoturbidimetric technology, a new line of specific proteins urinary tests from Sclavo Diagnostics uses liquid, ready-to-use reagents in various packaging formats. It includes:
Bence Jones Proteinuria, which provides measurement of free and bound K and λ light chains in liquid chemistry and may be useful in the overall evaluation of tubular damages;
(Micro) Albuminuria, a strong marker of glomerular damages, is a most valuable indication for diabetes, arterial hypertension and gravidic gestosis, in addition to renal diseases; ∝-1-Microglobulin and β-2-Microglobulin efficiently detect any tubular damages and their increased level can additionally help identifying Bence Jones Proteinuria; Immunoglobulins G in urine helps the diagnosis, in the presence of albuminuria, of all forms of primary and advanced secondary glomerular disease; Transferrin is useful in pathologies such as renal failure, especially in case of glomerular deficiencies: by assaying urinary albumin and transferrin, it is possible to gain information on electric charge selectivity since both proteins have similar sizes but a different charge.
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Modular platform for digital Image capture, processing and analysis
, /in Product News /by 3wmediaSYIONS is a miniaturized modular diagnostic imaging platform, allowing users to quickly and efficiently generate all types of image data from in-vitro diagnostics devices for use in scientific and clinical settings. SYIONS enables the quick and cost-effective implementation of applications in the areas of live cell imaging, flow cytometry and molecular diagnostics.
The modular system solution combines proven Jenoptik modules such as LED illumination, optical elements, digital cameras and auto-focus, as well as X/Y scanners, electronics, and software, to enable efficient imaging solutions that provide the user with images of the highest quality and ensure easy integration into the software system environment of medical or laboratory devices. Moreover, with Jenoptik’s own modular software, work processes can be performed consistently and efficiently across various operating systems. For instance, with the help of Jenoptik’s SYIONS platform, the examination of cells or tissue samples can be automated quickly and reliably. Devices are decreasing in size while, at the same time, performance data is improving and reliability is increasing. Due to the standardization of the individual modules, these devices can now be produced cost-effectively in smaller production runs.
SYIONS is made up of various established Jenoptik technologies, which have been combined to create a complete custom solution that is tailored to the individual needs of clients, including their system requirements and application needs. This complete system is significantly smaller than conventional microscopes and imaging systems, meaning it can be quickly and easily integrated into the client’s laboratory equipment, whether existing or yet to be developed.
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