C396 Sebia copy crop

Capillary electrophoresis analyser now connected to lab automation system

Sebia’s latest generation instrument, Capillarys 3 TERA, is now connectable to the Inpeco automation systems, available under the FlexLab brand name and as Aptio by Siemens. This analyser offers a large menu of tests for the diagnosis and follow-up of myeloma, diabetes and hemoglobin disorders. Two assays are now connectable to Inpeco automation: HbA1c and Serum Protein Electrophoresis. Other tests such as Serum Immunotyping and Hemoglobin electrophoresis will follow soon.
The Capillarys 3 TERA TLA connection with FlexLab opens new opportunities for lab automation and brings the capillary electrophoresis analyser closer to the core clinical laboratory workflow. Designed as a point-of-space connection, Capillarys 3 TERA TLA can process serum and whole blood at the same time thanks to a specific development on FlexLab.
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C400 Diesse

Single test multiparametric system for immunometric assays

Now featuring an autosampler accessory that enables the automatic pipetting of samples and automatic start of the run, the Chorus TRIO multiparametric system consolidates infectious diseases and autoimmunity tests on a single system.
The Identi-System Bar-Code Concept ensures the elimination of human errors in the preanalytical phase. Results are reported early, reducing turn-around time and it is possible to combine any kind of test in the same run. The minimal manual operation consists of just 3 steps: dispensing the serum into the device; placing the device in the instrument and simply pressing RUN as the instrument is programmed by the device’s bar-code label.
The single test device contains all the reagents necessary to perform the assay; there are no hidden costs or waste of reagents. A master curve procedure with 1-point calibrator is included in the kit. Packaging comes in sets of 36 or 12 devices according to the type of test. The random access instrument has a capacity of up to 30 different assays per run and may be operated in batch mode. Other features include touch-screen LCD, internal bar-code reader, built-in thermal printer and a multi-wavelength photometer (450, 650 nm). The instrument provides storage of all data of the last 20 sessions as well as a bidirectional connection to a host computer (RS-232 serial port). The autosampler accessory takes up to 30 primary tubes on board with disposable tips and incorporates an internal bar-code reader. Its compact design allows it to upgrade the Chorus instrument with no extra room required. 
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C401 77 Elektronika

Complete urine laboratory system

The new generation of the popular automated urinalysis system that combines a urine chemistry analyser and a urine sediment analyser is introduced. The LabUMat 2 is a high-throughput, automated urine chemistry analyser that is able to evaluate 10 chemical and 3 physical parameters of urine samples. The UriSed 3 PRO is an automated urine sediment analyser with a novel optical system combining bright-field and phase contrast microscopy, detecting 18 sediment particle types without the need of any liquid reagents. The efficiencies of the LabUMat 2 and the UriSed 3 PRO are maximized when these instruments are used as one walk-away system dealing with the workload of big laboratories. The automated technology improves diagnostic quality by increased reproducibility and accuracy and also improves productivity by eliminating the time-consuming procedure of manual sample preparation.

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C394 SSI image2

S. pneumoniae and L. pneumophila rapid test

Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and Legionella pneumophila causes costly hospital and ICU admissions. It is difficult to clinically distinguish between the two bacteria and due to different treatment of the diseases, guidelines recommend double testing.
The ImmuView Antigen test makes it now possible to readily distinguish between both microorganisms in patients with presumed infection, allowing clinicians to initiate the correct antibiotic treatment. It is the only rapid test that identifies both Streptococcus pneumoniae and Legionella pneumophila in one single test for urine and CSF samples. ImmuView is very simple to use, does not require any special equipment, and provides a result in just 15 minutes. In fact, in only 3 simple steps, it determines whether the patient has a double infection, a S. pneumoniae infection, a Legionella infection, or none of these.  

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C395 Fujirebio crop

Alzheimer markers assays

The Lumipulse G pTau 181 and β-Amyloid 1-40 assays are the latest additions to Fujirebio’s fully automated Neuro product line and complement the previously launched Lumipulse G Total Tau and β-Amyloid 1-42 assays. These assays are intended to measure β-Amyloid1-42, β-Amyloid1-40, total Tau and pTau181 in cerebrospinal fluid (CSF). Altogether, these four CSF markers support the diagnosis of Alzheimer’s disease, with the β-Amyloid1-42 / β-Amyloid1-40 ratio additionally being able to reduce the effect of inappropriate pre-analytics. These four assays are now available and can be run on the LUMIPULSE G600II and G1200 instruments. In comparison to the company’s INNOTEST predecessor assays, these newly CE-marked Lumipulse assays use the same well-established antibodies and show an improved performance. Low volume tests, like CSF biomarker analyses, generally benefit from the Lumipulse cartridge principle where one sample equals one test (per analyte), avoids wastage of reagents and the need for batch-testing.
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Randox Reagents Webvertorial Image CLI December 2019

Extend your lipid testing profile with Randox

Cardiovascular disease caused by atherosclerosis is the leading cause of morbidity and mortality in Western countries. Atherosclerosis involves the hardening and narrowing of vessels in the systemic system. If the build-up increases, plaque rupturing may occur which may lead to myocardial infarction.
The mission of the National Lipid Association (NLA) “is to enhance the practice of lipid management in clinical medicine” as the current lipid testing panel consists of LDL-C, HDL-C and triglycerides. These traditional tests only detect approximately 20% of all coronary artery disease patients.  Advanced lipid testing is recommended to optimise patient treatment.
Randox offer a range of niche and superior performance lipid assays including sdLDL-C and Lp(a) to extend your lipid profile.
 
For more information go to: https://www.randox.com/lipid-testing-panel/
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C410 Coris

3GC hydrolysis activity test provides digital result

The rate of resistance to third-generation cephalosporins (3GC) in gram-negative nosocomial infections is increasing worldwide, forcing clinicians to adopt alternative treatment to face multi-drug resistant strains. Rapid confirmation of 3GC resistance remains nowadays a priority for microbiologists. Today, microbiological susceptibility cultures are largely used because of their simplicity and low cost. However, cultures are time-consuming, providing resistance profiles in up to 4 or 5 days. Although presented as interesting alternatives, biochemical colorimetric tests could be in some case difficult to interpret because they are based on a subjective reading of a colour change. To circumvent that issue, Coris BioConcept is currently developing a new diagnostic tool to measure 3GC hydrolysis activity on bacterial colonies or on positive blood culture broths. This new assay, based on a recently-patented original method, delivers an objective digital result compared to phenotypic colorimetric assays. Used as a frontline test on gram-negative culture, it is foreseen as the ideal tool to accelerate decision on the implementation of infection control plans. Coris BioConcept is a Belgian company developing and manufacturing in-vitro diagnostic tests. With this new product in the pipeline, Coris BioConcept is offering an additional solution to its already existing RESIST products (immunochromatographic tests for the precise determination of carbapenemase-expressing organisms), and tightening its position as a key player in the field of antimicrobial resistance diagnosis. www.corisbio.com

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C411 RPS diagnostics

POC test for acute respiratory infection in all-in-one format

RPS Diagnostics recently announced an updated CE mark of its FebriDx test, clearing the way for its immediate launch in the European Union and all countries recognizing the CE mark. FebriDx is a rapid, accurate, and simple to use point-of-care test that provides clinicians with a 10-minute assessment of the body’s immune response to an acute respiratory infection (ARI) directly from a fingerstick blood sample. The single use, disposable test identifies patients who have a clinically significant underlying infection and aids in the differentiation of viral and bacterial ARIs through the rapid detection of both Myxovirus resistance protein A (MxA) and C-reactive protein (CRP). MxA is an intracellular protein that becomes elevated in the presence of acute viral infection and CRP is a nonspecific inflammatory protein that is elevated in the presence of any clinically significant infection. Thus, unlike a standalone CRP test, MxA confers specificity to the test through the combined interpretation of the results.
The updated FebriDx test incorporates an all-in-one plastic housing technology that includes a built-in safety lancet, blood collection and delivery system, and integrated push button buffer delivery feature, which together, improve test convenience. The FebriDx test requires no additional equipment to perform or to interpret results. Through comprehensive analytical testing as well as a multicentre precision and reproducibility study, RPS Diagnostics successfully demonstrated equivalency to the previously CE-marked version of the product.
The timely FebriDx test results enable clinicians to formulate a targeted clinical management and therapeutic decision plan during the initial patient encounter. Antibiotic misuse is a complex global problem that leads to antibiotic resistance, avoidable adverse events, and contributes to rising healthcare costs, largely driven by diagnostic uncertainty and patient pressure. More than 50% of all antibiotic prescriptions are unnecessary and are generated in the outpatient primary and urgent care setting. In a recent study in the United Kingdom, FebriDx was shown to alter clinical management decisions in 48% of patients tested, and to reduce unnecessary antibiotic prescriptions by 80%. Each day that goes by without the implementation of a cost-effective solution is exacerbating the current global antibiotic crisis.
It is equally important not to miss treating an underlying bacterial infection as it is withholding unnecessary antibiotics from patients with clinically insignificant or viral infection. While most research and investment over the past decade has focused on rapid molecular testing to identify specific pathogens, FebriDx utilizes the body’s own immune system to provide a broad, fast, accurate, and cost-effective method to identify patients who may benefit from appropriate antibiotic therapy.

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C409 D Tek

Customized and automated kits for autoimmune diagnosis

BlueDiver Combi kits contain a dispenser of 24 nitrocellulose chips on which a specific antigen has been coated in a microdot-shaped format. In addition to the antigen, 2 built-in controls have been also coated on each chip. The antigens and controls are coated in triplicate spotting to ensure the quality and the validity of the results. The test is based on a classical Enzyme Immuno Assay (eia). The user can select (out of more than 50 different antigens) and combine antigen chips (up to 6) to create a personalized immunodot test. The BlueDiver Combi therefore offers complete flexibility and customization to end-users.The BlueDiver Combi kits are automated on the BlueDiver instrument. The complete processing time lasts just 1 hour. The semi-quantitative results can be obtained thanks to the BlueScan scanner and Dr DOT software.

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C406 Cellavison crop

Digital cell morphology analyser

CellaVision DC-1 is the newest addition to the CellaVision family of analysers. It has been custom-designed to meet the specific needs of smaller low-volume hematology labs – enabling them to implement the best-practice digital methodology for performing blood cell differentials that many large labs today regard as standard practice.
CellaVision DC-1 is a semi-automated single-slide analyser that, although smaller, works just like the company’s existing analysers. A single slide is loaded onto the CellaVision DC-1 for processing. During processing the slide is automatically positioned under the microscope, the monolayer is identified, cells are located, and high-quality digital images are captured. Innovative image analysis technology delivers a pre-classification of white blood cells and a pre-characterization of red blood cell morphology for review and verification by the medical technologist or pathologist on a computer screen. Structured interfaces, smart functionalities and embedded tools help speed up the review process while promoting accuracy and consistency.

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