Launched under the SCIEX Diagnostics brand, the Triple Quad 4500MD and QTRAP 4500MD LC/MS/MS systems are expected to be available in the US and select EU countries in September. The new 4500MD series offers exceptional sensitivity and faster data acquisition over previous systems allowing clinical customers to obtain reliable results so physicians and patients have accurate answers quickly. The 4500MD series is a flexible LC/MS/MS platform that offers enhanced performance, improved sensitivity and faster data acquisition, to enable customers developing their own applications to validate methods that require lower detection limits or higher throughput, with the peace of mind afforded by a regulatory compliant solution. As scientific understanding progressively evolves into improved clinical diagnostic testing, diagnostic customers who develop their own assays are turning to fast, sensitive instruments to perform routine tests with high efficiency and cost savings.
Read more

Accurate and precise HDL and LDL cholesterol measurement is necessary for the effective diagnosis and treatment of lipid disorders. It is of greater importance however that the assays used for such diagnosis are capable of measuring HDL and LDL cholesterol not only for normal samples but abnormal samples too. The Randox HDL cholesterol reagent uses a direct clearance method for HDL cholesterol measurement. This method gives improved accuracy and reproducibility when compared to alternative measurement techniques due to the fact that all non-HDL cholesterol components such as vLDL, chylomicrons and LDL cholesterol are removed from the sample in the first reaction step- these components are not masked as in other HDL measurement methods. This is significant as it has been noted that when dealing with samples with high triglyceride or bilirubin levels, masking methods cannot clearly differentiate between HDL and non-HDL cholesterol components – effectively negating the effects of the test. Due to the fact Randox HDL cholesterol uses a clearance method these interferences are not an issue. In the second step of the reaction, HDL cholesterol is specifically measured resulting in a high degree of accuracy, even with abnormal samples.
The Randox LDL cholesterol assay also utilizes the clearance method for the accurate diagnosis of patient samples. The advanced reagent formula enables rapid clearance of all non-LDL lipoproteins from a sample, enabling the diagnosis of LDL cholesterol only. Furthermore, patient samples where diabetes, liver disease or high triglyceride levels are a concern can be accurately measured. The Friedewald calculation is often used in LDL cholesterol measurement however the accuracy of this method is inadequate due to its dependency on “normal” triglyceride levels. At high levels of triglycerides a large number of samples are misclassified using the Friedewald calculation leading to significant discrepancies between calculated LDL cholesterol and the true value. The Randox LDL cholesterol clearance method eliminates this problem and offers a superior alternative which ensures truly accurate results are produced, even with abnormal samples. Further beneficial features offered by the assays include liquid ready-to-use reagents; extensive measuring ranges ensuring abnormal analyte concentrations; applications detailing instrument specific settings for a wide range of clinical chemistry analysers; excellent on-board stability, minimizing reagent waste; wide variety of kit sizes offering greater choice.  

Read more

The MiniBeadbeater-24 cell disrupter disrupts and homogenizes all cell types, from bacteria and spores to animal and plant tissues. Cell lysis takes place in sealed 2 ml microvials containing glass or ceramic beads. Nucleic acids and proteins are isolated in 1-2 minutes of beadbeating. The ultra-high energy shaking machine processes up to 24 samples, has variable speed for special applications and simple controls. Essential for PCR methodologies, the MiniBeadbeater-24 uses disposible vials and beads, thus eliminating any possibility of cross-contamination between samples.

Read more

This testing system is designed for accurate measurement of Hemoglobin (Hb) and Hematocrit (Hct) in whole blood. It provides reliable results in just 15 seconds and requires only a 10 µl drop of blood. The handheld Hb meter is ideal for any point of care testing. The meter can read test strips and test devices (test cartridges) accurately, and both options are CE marked. The test strip is more affordable, while the test device features a deluxe design and is FDA cleared. This system is suitable for blood donor screening in blood banks, as well as physician offices, labs and community health centres. This convenient Hb testing system will make not only Hb testing but also anemia monitoring more accessible and affordable to people worldwide.

Read more