The new CoagL autoanalyser from DIAGON is the lastest addition to its portfolio of specially designed high quality hemostasis testing systems. Coag systems offer advanced, flexible and efficient automation for routine and specialilty testing coagulation labs and is supported by the same test technologies, reagents, cuvettes and consumables with low operation and maintenance costs. CoagL is a compact 4 channel coagulometer designed to include everything that could be improved in its category: it has extremely user friendly software with a high level of customization, offers real-time and post-run curve analysis, random access, reflex testing, and first tube preanalytical optical interference check. The company’s product range also includes a convenient and sensitive photo-optical CoagS POC INR test using recombinant technology, high tech Coag2D and Coag4D multichannel manual coagulometers and the 300 PT test/hour CoagXL fully automated coagulometer. All systems come with a complete reagent system, controls and calibrators both in liquid and lyophilyzed formats.  Diagon offers Coag Systems for distribution and for customized OEM cooperation.

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A new range of immunoblot profiles allows determination of IgG antibodies against foods and food additives in patient serum samples. Testing for IgG antibodies can help to establish if a food intolerance is behind chronic symptoms such as diarrhea, constipation, bloating, nausea, migraine, asthma, eczema, arthritis or fatigue. If high concentrations of IgG antibodies against a particularly food are identified, elimination of the offending substance from the diet may help to relieve symptoms. The EUROLINE profiles include 108 or 216 foods and food additives, grouped into the categories gluten- containing cereals, gluten-free cereals and alternative foods, meats, dairy and egg, fruits, herbs and spices, nuts and seeds, vegetables, legumes, salads, mushrooms, fish and seafood and other foodstuffs such as yeasts, honey, coffee and black tea. Only small volumes of patient serum are required for the analysis, just 40 μl for 108 results. Results are evaluated semiquantitatively using four calibrators corresponding to the WHO reference serum 1st IRP 67/86. IgG-mediated food intolerance results from increased permeability of the intestinal wall, the so-called leaky gut syndrome. Food components pass into the bloodstream, inducing the production of IgG antibodies and the formation of immune complexes. The complexes are deposited in tissues, leading to inflammation and aggravation of existing conditions. Symptoms of food intolerance occur hours to days after ingestion of the food and can manifest in the entire body, not just the gastrointestinal tract. The relevant IgG subclasses in chronic inflammatory processes are IgG1, IgG2 and IgG3, whereas IgG4 plays a role in classic IgE-mediated allergies.
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AP22 IF BLOT ELITE is a fully automated system for ELISA, IFA and BLOT methods. The instrument is able to run 2 ELISA microplates with 8 tests on line, 16 IFA slides or  24 blot strips,  starting from the sample dilution and dispensing, reagent dispensing, incubation , washing through to dot imaging processing with assessment for each strip; the software provides the data record and patient report.

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Based on an intelligent design and featuring SmartKit reagent loading technology, the Agility automated ELISA system emphasizes simplicity with an extremely intuitive, easy-to-use interface that enables effortless navigation. The system supports several major error-proofing advances, including a comprehensive monitoring system to measure consumable levels and extensive bar coding to eliminate manual data entry. The use of innovative direct-load reagent SmartKits streamlines front-end preparation and minimizes hands-on reagent loading, significantly reducing overall assay times and providing full walk-away freedom. Up to 16 SmartKits and 12 plates can be stored on-board for simultaneous runs. The system utilizes three precision robotic arms – one for sample pipetting, one for reagent pipetting and another for transporting plates and consumables – to obtain maximum process efficiency and unparalleled precision while eliminating nearly all manual steps and reducing the potential for human error. The Agility ELISA system combines ingenious design, total automation and an innovative approach to reagent loading that boosts productivity and minimizes hands-on time.

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