Unlike traditional pipettes which utilize a single rotating plunger to set volumes, the new EVOLVE manual pipette range from INTEGRA features an innovative approach that allows users to set volumes more than ten times faster. Available in single, eight and twelve channel formats, covering a volume range of 0.2 – 5,000 ?l, the ultralightweight, well balanced design of the EVOLVE enhances productivity and comfort even during prolonged pipetting sessions.
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Based on an intelligent design and featuring SmartKit reagent loading technology, the Agility automated ELISA system emphasizes simplicity with an extremely intuitive, easy-to-use interface that enables effortless navigation. The system supports several major error-proofing advances, including a comprehensive monitoring system to measure consumable levels and extensive bar coding to eliminate manual data entry. The use of innovative direct-load reagent SmartKits streamlines front-end preparation and minimizes hands-on reagent loading, significantly reducing overall assay times and providing full walk-away freedom. Up to 16 SmartKits and 12 plates can be stored on-board for simultaneous runs. The system utilizes three precision robotic arms – one for sample pipetting, one for reagent pipetting and another for transporting plates and consumables – to obtain maximum process efficiency and unparalleled precision while eliminating nearly all manual steps and reducing the potential for human error. The Agility ELISA system combines ingenious design, total automation and an innovative approach to reagent loading that boosts productivity and minimizes hands-on time.
DIAsource ImmunoAssays has announced the CE-IVD certification of 6 parameters of the ToRCH panel: Toxoplasma IgG Elisa # KAPDTOXOG; Toxoplasma IgM Elisa # KAPDTOXOM; CMV IgG Elisa # KAPDCMVG; CMV IgM Elisa # KAPDCMVM; Rubella IgG Elisa # KAPDRUBG; Rubella IgM Elisa # KAPDRUBM. The new assays have a common protocol (only 10µl of sample required) which allows their easy adaptation to most of the common automated ELISA platforms e.g. Stratec Gemini. The “IgG Elisa” are quantitative assays and include one control. The “IgM Elisa” are based on the IgM µ-capture technique, are qualitative assays and include three controls. Moreover, their high diagnostics specificity and sensitivity allow respectively the accurate detection of acute infection and the reduction of false positive cases. Lastly, the colour coded kit reagents offer easy recognition in a manual setting.
Among the most clinically significant multidrug-resistant bacteria are carbapenemase-producing Enterobacteriaceae. Because these bacteria usually remain susceptible to polymyxins, interest in this old class of antibiotics has been recently renewed. However, the increasing use of colistin explains why Enterobacterial strains resistant to colistin are increasingly reported worldwide. Currently available polymyxins susceptibility methods are fastidious and time-consuming (24 hours). ELITechGroup Microbiology releases its new Rapid Polymyxin NP test proposed as a rapid, reliable and cost-effective test to detect polymyxins (polymyxin E or Colistin, polymyxin B) resistant Enterobacteriaceae. This test is based on the detection of the glucose metabolization related to bacterial growth in presence of a defined concentration of colistin. Formation of acid metabolites consecutive to the glucose metabolization is evidenced by a colour change (orange to yellow) of a pH indicator. The Rapid Polymyxin NP test is easy-to-perform, very sensitive and specific. It can detect in only a couple of hours polymyxin-resistant and –susceptible isolates from any enterobacterial species, regardless of the molecular mechanism of polymyxins resistance. This test offers the possibility of detecting polymyxins resistance from bacterial cultures before any antimicrobial drug susceptibility testing results are obtained. Results are obtained at least 16 hours sooner with this test than with the reference broth microdilution method. It is as reliable as the reference dilution technique but much less cumbersome and is not based on diffusion of large polymyxin molecules in agar, which therefore prevents false susceptibility results. The rapid polymyxin NP test can be used to screen resistance to polymyxins in countries facing endemic spread of carbapenemase producers and for which polymyxins are last-resort drugs. But it also enables anywhere else the rapid identification of carriers of polymyxin resistant isolates, thus leading to rapid implementation of adequate hygiene measures to control their spread.
BioSystems is introducing BA200, a benchtop analyser with a real throughput of 200 t/h with any combination of methods and parameters (or up to 286 t/h including 4-channel ISE option), washing station, barcode identification and ISE capabilities. Offering the highest loading capacity of its segment, with 88 positions barcoded, that could be adjusted with specific adaptors to be used either as reagent, sample (primary or pediatric tubes), standard or control, it provides maximum configuration flexibility to adapt to the workload of any small or medium size laboratory, from routine to special chemistries. A BioSystems’ patented LED light source allows a precise focus in the reading spot area with no energy loss, increased signal and a sustained performance over its lifetime, over 50,000 hours of continuous operation without change of intensity, reducing their maintenance to almost zero. Also, the newly developed Dynamic Baseline procedure allows multiple readings to be made as the rotor is spinning to obtain highly accurate blank readings used to offer higher reliability for low absorbance values, thus improving significantly the CV% of the test at low values. Finally, the BA200 system introduces also a dedicated range of reagents in package size adequate to small and medium laboratories (but also fully compatible with BA400 system), ensuring the highest performance and on-board stability.
Cystatin C (CysC) is an endogenously expressed, non-glycosylated protein known as a sensitive biomarker for early detection of kidney failure. Beside its obvious advantages over creatinine in estimating the glomerular filtration rate, it has not yet found its way in clinical routine. One major reason for this was the lack of a suitable standardization process, which changed in 2010 with the availability of the certified reference material, ERM-DA471/IFCC. DiaSys achieved excellent results in a recent multicentre study with its Cystatin C FS assay with major advantages over competitors. The results showed that among all tested immunoturbidimetric CysC assays, only the DiaSys test met the performance criteria at the four relevant concentrations. Cystatin C FS is a particle-enhanced immunoturbidimetric test featuring outstanding analytical sensitivity, high prozone security and excellent onboard/calibration stability.
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The MERGITE! device from EUROIMMUN increases the efficiency and reproducibility of indirect immunofluorescence tests (IIFT) by providing automated washing of incubated slides. In the high-throughput washing procedure, up to 50 substrate fields are washed in parallel in approximately 40 seconds (instead of 5 minutes with manual washing). The direct and controlled liquid flow provides fast, meticulous washing which is gentle on the substrates. Cross contamination is prevented by separate washing of each field. The standardized, predefined wash programmes ensure a consistent washing quality and high reproducibility. Since manual drying of slides is no longer necessary, the risk of damage to the substrates is substantially reduced. The automated washing procedure reduces wash buffer usage by up to 50% compared to manual washing and eliminates the need for beakers, cuvettes and paper towels. Specially developed carriers provide efficient and safe handling of slides during incubation, washing and covering. The device has an intuitive user interface for easy use and minimal familiarization time. Its integrated touch screen enables independent operation without connection to a PC. The compact tabletop device requires very little standing space in the laboratory. MERGITE! is part of a complete package from EUROIMMUN for fully automated processing, microscopy and evaluation of IIFT.
Almost 70% of clinical labs process mistakes happen during the sample collection phase, a crucial step for the entire diagnostic process. Today ProTube ensures unparalled reliability and complete biologic sample traceability, along the entire blood sampling phase. Starting from the positive patient identification to correct tube selection and labelling automation, ProTube tracks the whole sample process, through advanced data analytics systems and LIS real-time communication. Correct patient identification, no tube mismatches, process automation and 100% traceability are the key steps that lead to an improvement in the clinical lab workflow; ProTube allows the operator to save time in checks and manual operations, thus enabling the management of 40% more patients per hour (if compared to a centralized labelling system, see Plebani paper on “Pre-analytical phase” in Clinical Chimica Acta, 2015).
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The sciREADER FL2 offers a high resolution imaging technology and easy data analysis inherited from the company’s sciREADER CL2. Equipped with up to 3 fluorescent channels it can be applied for all commonly used blue, green and red fluorescent dyes that are excited using LEDs with specific wavelengths. It’s the only reader on the market which allows for high quality imaging of 96 well plates for standard fluorescence single parameter assays and multiplexed arrays. Operators benefit from exceptional ease of use software including automated spot finding, image analysis and evaluation of single arrays or array batches. Customization of array layout, analysis and reporting makes it a suitable tool for clinical diagnostics and life science research. With the seamless integration of spotting patterns like GAL files and unique software features for spot adjustment, re-analysis and interpretation of analysis results, the sciREADER FL2 offers a complete solution for multiplexed diagnostics.
November 2025
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