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Archive for category: Product News

Product News

cytosmart Organoid Counting software

CytoSMART Technologies introduces automated organoid counter

, 23 December 2020/in Product News /by 3wmedia

CytoSMART Technologies has launched an automated organoid counter. The software application detects organoids using bright-field image analysis and runs on the Corning Cell Counter, a CytoSMART product.
Manually counting organoids is a routine part of laboratory operations, but is time consuming and user dependent. To overcome these issues CytoSMART has introduced this organoid counting application.
Joffry Maltha, CEO at CytoSMART Technologies, explained: “The 3D cellular structures that are formed in organoids have great potential in drug discovery and developmental biology. This has fuelled the ever-growing interest in culturing new sub-types of organoids and optimization of current protocols. Growing organoids does however take a substantial amount of time and skill. We believe that implementation of an automated solution for organoid counting can really speed up day-to-day work in the lab and is a logical step towards further implementation of organoids in cell culture-based research.”
The main features of the CytoSMART Organoid Counter are:

  • The main features of the CytoSMART Organoid Counter are:
  • Low-cost – works with a common reusable glass hemocytometer. No consumables required.
  • Precise – software allows for data gating and image selection for statistical analysis.
  • For more information, visit: https://cytosmart.com/products/organoid-counting

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1 PRODUCT BIO RAD

Bio-Rad introduces StarBright Violet 515 Dye for flow cytometry

, 23 December 2020/in Product News /by 3wmedia

Bio-Rad Laboratories, a global leader of life science research and clinical diagnostic products, has introduced StarBright Violet 515 (SBV515) Dye, the first of a new range of unique fluorescent nanoparticles, for use in flow cytometry. Star- Bright Dyes are conjugated to a growing range of antibodies and are compatible with most flow cytometers and experimental protocols.
The StarBright Violet 515 Dye with an excitation maximum at 401 nanometre and emission maximum of 516 nanometre offers researchers improved brightness to resolve rare and low antigen density populations more easily. It has a narrow emission profile to reduce spillover into neighbouring filters and minimal excitation by other lasers, making it suitable for inclusion in multicolour panels.
The dye is not susceptible to photobleaching, delivers high lot-to-lot reproducibility, and is stable at 4°C with no loss of signal to help ensure consistent staining and deliver reliable results. It has been tested in many common staining buffers and there is no requirement to use a special staining buffer, permitting easy integration into common experimental protocols without compromising performance. StarBright Violet 515 Dye is compatible with Bio-Rad’s ZE5 Cell Analyzer, S3e Cell Sorter, as well as other cytometers, and it is suitable for both conventional and spectral flow.
Mike Blundell, Bio-Rad Product Manager, Life Science Group, commented: “StarBright Violet 515 Dye is brighter than other common dyes that emit at similar wavelengths. The dye is flexible enough to fit into any flow cytometry panel, allowing researchers to multiplex with ease regardless of flow cytometer and experimental protocol, and it offers a superior alternative for fluorophores that have emission maxima between 500 and 550 nanometres.”
For more information, visit: www.bio-rad-antibodies.com/starbright
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2A PRODUCT BIO RAD

Biorad introduces Platelia SARS-CoV-2 Total Ab assay

, 23 December 2020/in Product News /by 3wmedia

As COVID-19 continues to impact countries worldwide, accurate screening is needed to establish serological status of different populations. Bio-Rad now offers the Platelia SARS-CoV-2 Total Ab assay, for the detection of total anti-nucleocapsid antibodies (IgM, IgA, IgG) to SARS-CoV-2. In one test, the assay helps identify the immune response to coronavirus SARS-CoV-2, the virus associated with COVID-19.
For more information, visit: https://info.bio-rad. com/cdg-sars-cov-2-ous?WT.mc_id=200814028804
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BioChromato

BioChromato introduces sterile 96-well plate seal for cell culturing

, 23 December 2020/in Product News /by 3wmedia

BioChromato has introduced a gamma sterilized version of its popular RAPID Slit Seal for scientists looking to eliminate solvent evaporation from samples when culturing cells in 96-well microplates.
The RAPID Slit Seal is a proprietary self-closing microplate seal that returns to its original state even when punched with an HPLC or LC/MS autosampler. As a result, loss of volatile solvents from samples is eliminated.
In addition, with RAPID Slit Seal, insertion of pipette tips and sampling needles is easier and can be achieved without dragging.
In addition, with RAPID Slit Seal, insertion of pipette tips and sampling needles is easier and can be achieved without dragging.

  • For further information, visit: www.bicr.biz/product/consumables/rapid-slit-seal

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https://clinlabint.com/wp-content/uploads/sites/2/2021/01/BioChromato-scaled.jpg 1308 2560 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-12-23 00:00:002020-12-23 00:00:00BioChromato introduces sterile 96-well plate seal for cell culturing
3 PRODUCT BD

BD granted FDA clearance for BD FACSLyric Flow Cytometer with newly integrated BD FACSDuet Sample Preparation System

, 23 December 2020/in Product News /by 3wmedia

BD (Becton, Dickinson and Company), a leading global medical technology company, has received 510(k) clearance from the U.S. FDA for the BD FACSLyric™ Flow Cytometer with the Integrated BD FACSDuet™ Sample Preparation System.
The new integrated system enables clinical laboratories to fully automate the sample to answer process and improve their efficiency by reducing errors and limiting the manual user interactions required to run assays on the BD FACSLyric™ Flow Cytometer.
The BD FACSDuet Sample Preparation System builds new capabilities into the BD portfolio of clinical flow cytometry solutions offering a pre-analytical system, that combined with the BD FACSLyric Flow Cytometer is the first truly walkaway sample-to-answer solution for clinical labs.
Physical integration between the BD FACSDuet Sample Preparation System and the BD FACSLyric Flow Cytometer allows technicians to load samples and reagents’ samples are acquired and analysed on the BD FACSLyric Flow Cytometer. Data integration using the BD FACSLink™ Middleware Solution offers bidirectional communication between the instruments and connectivity with laboratory information systems.
The BD FACSLyric™ Flow Cytometer with the integrated BD FACSDuet™ Sample Preparation System is now available as an in vitro diagnostic (IVD) system in the United States as well as countries recognizing the CE-IVD certification, which was achieved in March 2019.
For more information, visit: www.bdbiosciences.com/en-us/instruments/ clinical-instruments/clinical-cell-analyzers/facslyric
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3B PRODUCT HAEMATEX

Haematex introduces Direct Oral Anticoagulant “dots”

, 23 December 2020/in Product News /by 3wmedia

Haematex has introduced Direct Oral Anticoagulants (DOACs) in the form of rapidlydissolving 500 nanogram “dots” on disposable plastic strips. They are stabilized in a thin, flexible film supported on a clear, inert backing. The film dissolves within 2 minutes in 1 ml of fluids such as blood, plasma or urine, thereby transferring the compound into samples. The effect of such inhibitors on individual plasmas can then be assessed using clotting or chromogenic tests.
The new supported film technology is adaptable to any potent, stable agent. It allows a library of compounds to be held as a flat collection rather than in vials, thereby allowing for more easy transport and storage.
Dabigatran-like, edoxaban-like, betrixabanlike, rivaroxaban-like and apixaban-like compounds are available. Heparin (0.3 Iu) is also available. All “dots” are colour-coded for recognition. They are especially useful for checking the effect of DOAC-extracting agents such as DOAC Stop™. They are also available in smaller sizes and in mini-tubes.
For more information, email: info@haematex.com or visit: www.haematex.com
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biochromato C1 Smart Evaporator

BioChromato’s compact benchtop evaporator for DMSO & DMF samples proves popular with labs

, 23 December 2020/in Product News /by 3wmedia

BioChromato, a respected Japanese manufacturer of high-quality products for chemical laboratories, reports that it has installed more than 1200 units of its Smart Evaporator C1 – a compact system that delivers rapid concentration or complete drying of samples in even high boiling solvents such as DMSO, DMF or water.
Designed to be easy to use, the Smart Evaporator C1 is an affordably priced system optimised to concentrate or dry single samples directly from any tube or vial (up to 32 mm neck diameter).
Drawing upon BioChromato’s patented spiral plug evaporation technology, the compact, benchtop Smart Evaporator C1 offers fast and effective evaporation in tubes or vials without solvent bumping thereby eliminating risk of sample loss, cross contamination and saving researchers time.
Proven to be the ideal lab tool for simple removal of high boiling point solvents, the C1 also excels at safe drying temperature sensitive compounds and efficient evaporation of small volume samples.
The Smart Evaporator C1 is optimised to handle solvent volumes up to 40 mL which can be extremely useful for concentrating compounds after organic synthesis or drying analytical samples at relatively high speeds. The versatile C1 can also take small tubes and vials (e.g. 1.5mL) where solvent volumes can be as little as 0.1ml (or less).

  • For more information, visit: https://biochromato.com/smart-evaporator/

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4 PRODUCT DIASYS

DiaSys introduces Procal-citonin FS fluid-stable, particle-enhanced immunoturbidimetric assay

, 23 December 2020/in Product News /by 3wmedia

DiaSys has launched a fluid-stable, particleenhanced immunoturbidimetric assay for determination of procalcitonin (PCT) in serum and plasma on clinical chemistry analysers.
Procalcitonin FS offers high precision at clinical cut-off levels for sepsis with a measuring range from 0.2 ng/mL to 50 ng/mL. Procalcitonin FS has an outstanding onboard and calibration stability. No prozone effect was observed up to 1000 ng/mL.
The assay performance is complemented by high tolerance to endogenous interferents and common therapeutics used in sepsis management. Method comparisons of Procalcitonin FS show good comparability to established tests and present the new assay as a reliable alternative for clinical chemistry analysers.
For more information, visit: www.diasys-diagnostics.com/products/reagents/ immunoturbidimetry/reagent-details/227- procalcitonin-fs/reagent.show
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6C PRODUCT TRIMERO

TRIMERO’s Free Light Chain assays CE marked for testing Kappa and Lambda FLC

, 23 December 2020/in Product News /by 3wmedia

TRIMERO’s new generation of Free Light Chain (FLC) assays, called KLoneus, includes an IVD CE marked assay for testing Kappa and Lambda FLC in non-concentrated urine samples on Siemens’ BN nephelometric systems.
The main features of the assays are:

  • particle enhanced nephelometric method
  • specifically developed to assay urine samples
  • based on polyclonal specific antibodies
  • with antigen excess control using the pre-reaction feature
  • values traced to the European Reference Material ERM-DA470k/IFCC (Institute for Reference Materials and Measurements, IRMM), in order to ensure consistent results and good correlation with other methods (urinary B&F Light Chain nephelometric assays, and BJP estimation by densitometry).

KLoneus FLC assays are also available for Beckman Coulter’s IMMAGE nephelometers and for the most popular clinical chemistry analysers. Other available assays for Siemens’ BN systems include: C1q Complement, C5 Complement, C3 pro-activator (Factor B) and IgD Immunoglobulins.
For more information, visit: www.3diag.com
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amsbiopr272b

AMSBIO offers customised solutions for exosome-related research

, 23 December 2020/in Product News /by 3wmedia

AMS Biotechnology offers a comprehensive range of end-to-end services for exosome purification, characterization, and engineering.
Exosomes are small endosome-derived lipid nanoparticles, actively secreted by exocytosis in most living cells. Acting on tissues in both the local environment and further afield, they function as important signal carriers through their transport of RNA, proteins, lipids and DNA. Exosomes are involved in a wide range of normal and pathogenic processes, making exosome research crucial in multiple areas. Exosomes are a type of extracellular vesicle (EV) that show promise for use as unique drug carriers to deliver protease inhibitors to treat COVID-19.
In this application, EVs may provide targeted delivery of protease inhibitors, with fewer systemic side effects. More importantly, EVs are highly suitable for major aseptic processing and can be upscaled for mass production.
The Exosome Isolation & Quantification Service from AMSBIO provides reliable and reproducible isolation of exosomes from almost any biofluid ranging from plasma and tissue culture media to cerebrospinal fluid. Using this service, exosomes are isolated by ultracentrifugation and quality assessed using a NanoDrop spectrophotometer. Options are also available to isolate by differential/gradient ultracentrifugation, immunoaffinity, size exclusion chromatography, precipitation/low speed centrifugation.
For scientists interested in exosome miRNA isolation and sequencing, AMSBIO offer a service to extract RNA from exosomes, and subject it to the Small RNA-Sequencing. In addition, basic analysis will be performed on the raw data, and screening for specific miRNA can also be performed.
AMSBIO also offers analysis of exosome surface proteins using MACSPlex kit. For proteomics analysis, samples will be analysed by LC/Q-TOF mass spectrometry to characterize the peptides formed. The analysed samples are also differentially analysed using molecular features finder and mass profiler to determine changes in the peptide profile. The resultant MS/MS data from the selected peptides will be imported into Spectrum Mill proteomic server software to identify the protein that is consistent with the imported peptide sequence. Both NCBInr and Swiss-Prot databases are available to search for users of this service.
In addition, AMSBIO can undertake a wide range of exosome functional assays including exosome-induced cell proliferation, exosome induced collagen production, Exosome-induced inhibition of inflammatory cytokines and In vitro wound healing (scratch assay).

  • For further information, visit: www.amsbio.com/exosome-research-services

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Bio-Rad - Preparing for a Stress-free QC Audit

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