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Author Archive for: 3wmedia
Entries by 3wmedia
Tick-borne encephalitis virus arrives in the UK
Tick-borne encephalitis (TBE) is caused by the TBE virus (TBEV) and is primarily transmitted to humans through a bite from an infected tick. TBEV (a flavivirus) has three genetically and antigenically closely related subtypes: the European, Siberian and Far-Eastern. TBE is endemic in mainland Europe, Scandinavia and Asia, and has recently been found for the […]
Introducing serum apolipoprotein profiling for enabling precision cardiology: its time has come
To assess the risk of cardiovascular disease (CVD), 10 – year risk scores are calculated based on four serum lipids (total cholesterol, LDL-C, HDL-C and total triglycerides) and other (un)modifiable risk factors. Recently we proposed an apolipoprotein (apo) panel that provides more granular information regarding the specific type of lipid disorder. This extended information fits […]
Lipidomic profiling using liquid chromatography mass spectrometry
The past 15 years have shown a slow but steady expansion of the field of lipidomics, which pushes analysis beyond understanding of traditional lipids (HDL-C, LDL-C and triglycerides). This article aims to introduce readers to the world of lipidomics and the remaining hurdles involved in this exciting field. By Matthew W..K. Wong and Dr Nady […]
LC-MS/MS for profiling of urinary eicosanoids
The eicosanoids are a family of lipid mediators of pain and inflammation involved in multiple pathologies. Urine has become a useful, readily accessible biofluid for monitoring the endogenous synthesis of these metabolites. The clinical interest of eicosanoids requires their targeted determination, which, in turn, warrants the development of high-throughput analytical methodology such as liquid chromatography–tandem […]