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Insight into monocyte distribution width for sepsis diagnosis and COVID-19 prognosis
Sepsis requires fast treatment for the best outcome, but is notoriously difficult to diagnose. Monocyte distribution width (MDW) is a parameter that gaining traction in the diagnosis of sepsis and may also be useful in predicting severe outcomes from COVID-19 infection. CLI caught up with Lorenzo Maggia, Product and Scientific Senior Manager at Beckman Coulter Europe, and […]
Clinical Lab Microscopy & Imaging: Literature Review
Pixel-based analysis of pulmonary changes on CT lung images due to COVID-19 pneumonia Soya E, Ekenel N, Savas R et al. J Clin Imaging Sci 2022;12:6 doi: 10.25259/JCIS_172_2021
Dried blood spot microsampling in screening and monitoring of PKU
Since the 1960s, the use of dried blood spot (DBS) technology for newborn screening (NBS) and monitoring of patients with inherited metabolic disorders (IMDs) has become routine in most parts of the world.
Interpreting hematology results in pediatrics – a moving target?
Accurate interpretation of laboratory tests is essential to diagnosis and monitoring of many pediatric disorders. Hematology test results in children cannot be interpreted using adult reference intervals owing to the vast changes that occur throughout childhood from the neonatal period to adolescence. Consequently, the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) programme has recently […]
Point-of-care testing in the management of hemorrhage in cardiothoracic surgery
Cardiac surgery with cardiopulmonary bypass is associated with significant alterations in the hemostatic system. Standard laboratory coagulation tests are frequently used to assess coagulopathies and to guide hemostatic interventions. However, these tests present major limitations. Viscoelastic testing in conjunction with the implementation of a specific algorithm for coagulation management in cardiac surgery enables better control […]