Measurement of fecal calprotectin allows reliable discrimination of patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), an early detection of relapse in IBD-patients as well as an objective therapy monitoring. RIDASCREEN Calprotectin comes equipped with an economical calibrator for evaluation by 1-point calibration. Each kit additionally contains a set of 5 standards for quantitative determination of fecal calprotectin (FC) by means of a standard curve. The test is validated for manual as well as automated use. Optionally the RIDASCREEN stool collection tubes are available. They are prefilled with extraction buffer which allow for fast, clean and precise sample collection.
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For the measurement of fibrinogen concentration in plasma, Fibrinogen by BioSystems is a turbidimetry liquid bireagent method which is calibrated with a multipoint curve (lyophilized standard) and controlled with a lyophilized control plasma. Fibrinogen is a protein that is essential for blood clot formation. It is produced by the liver and released into the circulation as needed along with several other clotting factors. The concentrations of fibrinogen are increased in case of diabetes, obesity and inflammatory syndromes and are decreased in case of disseminated intravascular coagulation (DIC), fibrinolysis and genetic deficiency. In addition, elevated concentrations of fibrinogen can be involved in the pathogenicity of different cardiovascular thrombotic events. In recent years, a large number of prospective studies have shown that the fibrinogen concentration is a predictor of a variety of cardiovascular events, including stroke, myocardial infarction, leg ischemia (in arterial disease) and postsurgical arterial re-occlusion.

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Liquid electrolyte compensated-heparin secures the optimum quality of the blood gas sample during specimen collection. The basic version of the blood gas sample collection system is treated with ~ 50 I.U. anticoagulant.  Further heparin concentrations are available on request. Applicable to and compatible with all common blood gas analyser types, the sample collection syringes are unbreakable for maximum safety and efficient laboratory work. They are available in different volumes of 1ml or 2ml and Luer-Slip connector style as well as in Luer Lock version with 2ml volume and are single packed in sterile blister packaging. Special accessories include the SC-AUTOSTOP-Cap to avoid contamination during sample collection.

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Successful management of life-threatening, invasive fungal infections poses difficult challenges to clinicians. Routine therapeutic drug monitoring (TDM) for voriconazole may improve treatment response for patients with a poor response to therapy or toxicity. Voriconazole exhibits nonlinear pharmacokinetics, and significant inter-individual variability in serum concentrations due to polymorphisms in cytochrome P450 and drug-drug interactions. TDM has been considered for pediatric patients and for hematopoietic stem cell transplant recipients. Target trough levels 1 to 5.5 µg/mL have been proposed. The ARK Voriconazole Assay is a homogeneous enzyme immunoassay intended for the quantitative determination of voriconazole in human serum or plasma on automated clinical chemistry analysers. The measurements obtained are used in monitoring levels of voriconazole to ensure appropriate therapy. The ARK Voriconazole Assay is available worldwide outside the U.S.

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A new product category, Matched Antibody Pairs contain two monoclonal antibodies (a capture antibody and biotinylated detection antibody) that in combination enable scientists to develop their own sandwich assays. Matched Antibody Pairs for a range of targets are already available, for instance NGAL – for both Human (Monomer, Homodimer and Total) and Animal (Mouse, Rat, Dog, Pig, and Monkey) NGAL. NGAL is the earliest biomarker for acute kidney injury (AKI) in humans, and is the first renal biomarker that covers all the common animal models used in the pharmaceutical industry, making it possible to use the biomarker in the entire drug development process for toxicological studies. Other targets include Vitamin D Binding Protein, Glucagon, GLP-1 and other appetite regulating hormones, coagulation factors and complement system components. These products are for research use only.
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