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Archive for category: Product News

Product News

C347 Beckman CytoDiff Panel Kit OL

Flow cytometry software for hematology

, 26 August 2020/in Product News /by 3wmedia

Part of the company’s Hemato- Flow solution combining diagnostic reagent, hematology and flow cytometry hardware and IT expertise, Version 2 CytoDiff CXP Autogating software is designed to give laboratories added confidence in the use of flow cytometry in the routine hematology lab for the auto-validation of abnormal samples. Easy-to-use, the advanced Version 2 software further improves sub-population classifications. It adds new features, such as greater precision in the removal of potential interference and metrics that provide a new ‘confidence level’ on population classification. The new software simplifies the review process making it easier to validate results with greater certainty. HematoFlow with the CytoDiff five-colour antibody cocktail and CXP Autogating Software make it possible to use the precision of flow cytometry to deliver extended white blood cell (WBC) differential results with far greater consistency than manual microscopic assessment. The five-colour antibody cocktail, the CytoDiff, uses six monoclonal antibodies to establish the differential. The routine use of flow cytometry for validating abnormal samples can improve workflow and turnaround time as well as providing access to additional diagnostic information for patients. European laboratories are already working with Beckman Coulter to increase confidence in the routine use of flow cytometry in the hematology process for validating abnormal samples. Hospitals including University Hospital, Rennes and Bordeaux in France, Erasme University Hospital, Brussels, Belgium and several private labs are successfully adopting this approach. CytoDiff is not available for in vitro diagnostic use in the United States and other geographies.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C347_Beckman_CytoDiff-Panel-Kit-OL.jpg 106 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:19:222021-01-08 11:28:43Flow cytometry software for hematology
C399 Mindray inside

Cellular analysis line

, 26 August 2020/in Product News /by 3wmedia

Using unique technology, the SC-120 slide maker and stainer is able to make blood films, print the barcodes and other patient information directly onto the slides, stain them with different types of staining protocols and dry their wet surfaces. A total of 120 slides can be processed per hour. The stained slides, ready for microscopy, are loaded in cassettes located at the unloading area. The MindrayOmniLab CAL 8000 hematology system combines the BC-6800 hematology analyser with the SC-120 slide maker and stainer into one comprehensive workstation. With the possibility to include up to four BC-6800s and two SC-120s, the system can be scaled-up to meet the workload requirements of even large labs. Manual interruptions are minimized as the workflow of the SC-120 allows user-defined staining protocols and enables users to define decision rules. The resultant efficient workflow and higher reliability of the system reduce operating costs as well.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C399_Mindray_inside.jpg 62 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:19:222021-01-08 11:28:25Cellular analysis line
C371 Binding Site IMG 1776

ELISA for the quantitation of human IgG

, 26 August 2020/in Product News /by 3wmedia

Now available is a specifically formulated and optimized ELISA procedure for the quantitation of intact human IgG from matrices containing non-human proteins. The availability of such an assay meets the needs of clinical, biopharmaceutical, and medical researchers alike. The quantitation of IgG in cell culture supernatant is important in the selection of high yielding clonal cell line candidates for downstream scale-up fermentation. This ELISA utilizes sheep polyclonal antibody, specific to the Fc and light chain regions of human IgG for capture and detection respectively, ensuring not only intact human IgG is quantified. Coupled with that, the assay virtually eliminates any cross reactivity to common laboratory species (i.e. mouse, rat, primate) and to bovine serum proteins ensuring the utmost in test specificity. This unique ELISA procedure, displaying a measuring range for intact human IgG from 2.5ng/mL to 810ng/mL, also features a convenient operator-oriented packaging design, with sufficient reagents to perform 96 separate tests. It also includes all necessary calibration and quality control materials and offers exceptional performance characteristics, lot-to-lot consistency and shelf life stability.

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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C371_Binding-Site_IMG_1776.jpg 100 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:19:222021-01-08 11:28:37ELISA for the quantitation of human IgG
C050 AB SCIEX CLI June image of kit

Newborn screening mass spectrometry assay

, 26 August 2020/in Product News /by 3wmedia

Early detection and treatment of inherited metabolic disorders in newborns can lessen the severity of health problems, which could cause mental and physical disabilities or death, if undetected. The window of opportunity to determine if a baby is at risk of a serious or life-threatening condition before symptoms begin is small; therefore, test results for indicators of these disorders must be accurate, comprehensive and timely. To address this challenge, a newborn screening assay is now available in Europe only and is specifically designed for in vitro diagnostic use in conjunction with AB SCIEX mass spectrometry instrumentation for clinical analysis. With the new SCIEX IVD-MS kit for newborn screening, clinical diagnostic laboratories in Europe will be able to analyse panels of amino acids and acylcarnitines simultaneously – rather than one by one, as commonly done in hospitals today – and obtain information about indicators of multiple metabolic disorders from the same sample in a single run. Tandem mass spectrometry makes it possible to detect extremely low concentrations of compounds that can be used to indicate whether a baby is likely to have an inborn metabolic disorder. For example, mass spectrometry can be used to measure the markers for early screening of Phenylketonuria, or PKU. Babies diagnosed with PKU by their physician can be treated with a special diet of limited amounts of phenylalanine (Phe) to avoid build up in the blood and brain, which reportedly leads to mental disability. PKU reportedly occurs in nearly one out of every 10,000 newborns in most of Europe. With an accurate diagnosis, early treatment significantly decreases the severity of symptoms the child will experience as he/she grows up. Another example is the use of mass spectrometry-based newborn screening to find indicators of Medium-chain acyl-Coenzyme Dehydrogenase deficiency (MCAD). Twenty-five percent of children with undetected MCAD die the first time they have an illness. However, if the disorder is detected within days of birth, a treatment as simple as frequent meals and avoidance of fasting would set the child on a path to good health. Studies have shown that MCAD is most common among Caucasians from Northern Europe and includes numbers potentially as high as one out of every 4,900 in Northern Germany. The SCIEX IVDMS kit for amino acid and acylcarnitines in dried blood spots will be a fully validated mass spectrometry method with all the reagents necessary to prepare the sample for MS injection. Using these kits, healthcare professionals will be able to test dried bloodspots from a heel prick on newborns and run the test on an AB SCIEX 3200MD CE-marked IVD system where measurements of the analytes are translated into clinically relevant results, generated with easy-to-use software.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C050_AB-SCIEX_CLI-June_image-of-kit.jpg 150 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:19:222021-01-08 11:28:20Newborn screening mass spectrometry assay
C393 Chromsystems

Methylmalonic acid kit for vitamin B12 status determination

, 26 August 2020/in Product News /by 3wmedia

Now available is the MassChrom LC-MS/ MS kit for the analysis of methylmalonic acid (MMA) in plasma, serum and urine. Methylmalonic acid is an intermediate of amino acid metabolism and is regarded as an early and sensitive biomarker of vitamin B12. A deficiency leads to increased levels of MMA in plasma, serum and urine. The use of special Clean-up Tubes enables a quick sample preparation that removes interfering compounds effectively. False-positive test results are prevented by chromatographic separation of the isobaric compound succinic acid. Precision of results is ensured with stable isotope-labelled internal standards as well as the matrix-adapted 3PLUS1 Multilevel Plasma and Urine Calibrators.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C393_Chromsystems.jpg 115 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:19:222021-01-08 11:28:29Methylmalonic acid kit for vitamin B12 status determination
Greiner Bio One VACUETTE TUBE TOUCH Needle Indicator

Blood collection system

, 26 August 2020/in Product News /by 3wmedia

The VACUETTE TUBE-TOUCH is a safety product of the newest generation with an automated activation of the protective shield. This product is a further development of the already existing VACUETTE PREMIUM Safety Needle System. It was developed in close collaboration with users. The result is the VACUETTE TUBE-TOUCH Holder. The new name vividly captures the product’s functional capabilities. The safety mechanism is activated by placing the tube in the holder. In this way, needlestick injuries are automatically avoided. Apart from being easy to use, the VACUETTE TUBE-TOUCH is characterized by its newly designed protective shield, which is freely movable upon activation. Graduation marks have been added to the protective shield in order to easily demonstrate the position of the needle in the vein for the user. These marks show how far the needle is located in the vein. During removal of the needle from the vein, the protective shield automatically encloses the needle making the product practical, simple and safe. This product will be introduced this year in July at the AACC in Houston. Stand 4511.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/Greiner-Bio-One_VACUETTE-TUBE-TOUCH_Needle-Indicator.jpg 100 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:19:222021-01-08 11:28:41Blood collection system
C109 EDAN

POC immunoassay analyser

, 26 August 2020/in Product News /by 3wmedia

Multiple studies indicate a large number of diseases including cancer, infectious and cardiac diseases can be avoided, or even cured with early detection. The m16, a POCT magnetic immunoassay analyser with advanced magnetic bead-linked GMR (Giant Magneto Resistive) biosensor, can maximise and shorten the clinical laboratory’s turn around period, thereby providing faster, more accurate results and optimizing the clinical treatment’s efficiency.

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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C109_EDAN.jpg 106 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:18:522021-01-08 11:27:55POC immunoassay analyser
C095 Sakura 01

Automated and programmable microtome

, 26 August 2020/in Product News /by 3wmedia

Building on the principles of SMART Automation, Sakura Finetek introduces the next step in total laboratory automation, the Tissue-Tek AutoSection Automated Microtome for histopathology laboratories. The first of its kind, this fully-automated and programmable microtome aligns and trims blocks with optimal precision, section after section. AutoAlign, the core technology behind AutoSection, precisely orients blocks and dramatically reduces the risk of losing tissue. In addition, with AutoTrim technology, blocks are ready for sectioning in seconds. Another major benefit of automation and stress-free microtomy is the reduction of repetitive motion and the increase of staff satisfaction. AutoSection ensures consistent high-quality sectioning, preservation of valuable tissue, improved productivity and minimal repetitive motions.

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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C095_Sakura_01.jpg 533 800 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:18:522021-01-08 11:27:54Automated and programmable microtome
Alere FMHBP100 4

A new marker in Sepsis management

, 26 August 2020/in Product News /by 3wmedia

Sepsis is the body’s systemic inflammatory response to infection and can progress to severe sepsis, septic shock and ultimately multiple organ failure and death. There are over 18 million cases of severe sepsis worldwide each year with an estimated annual cost of treating sepsis in the US alone of $17 billion (€13 billion). Early and accurate diagnosis of severe sepsis is essential for the survival of the patient – for every hour that proper treatment is delayed, the mortality associated with severe sepsis increases by 7.5%. Heparin Binding Protein (HBP) is a new biomarker that has demonstrated utility in identifying patients at risk of developing severe sepsis. HBP is an inflammatory mediator secreted by neutrophil white blood cells in response to an infection. A recent study demonstrated that an elevated plasma HBP level was a good indicator of severe sepsis (with or without septic shock) with a sensitivity of 87.1% and a specificity of 95.1%. The new CE-marked HBP assay from Axis-Shield is a simple ELISA assay for the measurement of HBP in plasma samples.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/Alere_FMHBP100_4.jpg 89 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:18:522021-01-08 11:28:02A new marker in Sepsis management
C051 Diagenode Tests for MGTV pic

Complementary qPCR diagnostic tests for sexually transmitted infection

, 26 August 2020/in Product News /by 3wmedia

A CE-marked multiplex real-time PCR reagent targeting Mycoplasma genitalium and Trichomonas vaginalis is adapted to the most used qPCR automated systems usually dedicated to C. trachomatis and N. gonorrhoeae. This new kit can dramatically improve the diagnosis process for patients with sexually transmitted infection. The mg219 gene was found to be in all strains of M. genitalium and was highly conserved; it is coupled to the mgPa gene and T. vaginalis. A quick and accurate detection of pathogens causing various STIs can solve a lot of problems with regard to partner contamination and supports adapted antibiotherapy regimens. Molecular diagnostics enables an easier and more reliable diagnosis than traditional methods. Mycoplasma genitalium has been convincingly linked to non-gonococcal urethritis (NGU) and nonchlamydial-non-gonococcal urethritis (NCNGU); association of M. genitalium infection and pelvic inflammatory disease (PID) aft er termination of pregnancy is an independent and strong risk factor for both cervicitis and PID. Therefore, M. genitalium infection in women is associated with clinical manifestations and complications that in some instances are amenable to prevention and treatment.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C051_Diagenode_Tests-for-MGTV_pic.jpg 113 150 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:18:522021-01-08 11:28:12Complementary qPCR diagnostic tests for sexually transmitted infection
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Bio-Rad - Preparing for a Stress-free QC Audit

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