The Randox Acusera Immunoassay Premium Plus control covers a comprehensive 54 analytes.  The inclusion of routinely run tumor markers, therapeutic drugs and important parameters such as intact PTH and Vitamin D allows laboratories to dramatically consolidate the number of controls used while ultimately saving money.  As an assayed control instrument and method specific target values are provided for the most common instruments and methods.  

                         

• Lyophilised for enhanced stability
• 100% human serum providing a matrix similar to patient samples
• Ferritin and Vitamin B12 present at levels suitable for anemia monitoring
• Ultra low TSH levels in the level 1 control
• Third party control for an independent, unbiased assessment of performance
• Reconstituted stability of 7 days at +2-8^oC or 4 weeks at -20^oC

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Two new microarrays based on state-ofthe- art technology provide molecular genetic risk determination for the frequently occurring hereditary conditions thrombosis and haemochromatosis. The EUROArray FV/FII Direct accurately identifies point mutations in the factor V (factor V Leiden, 1691G>A) and/or factor II (prothrombin) gene (20210G>A), which are the most frequent genetic causes of thrombosis and embolism. Mutations in the HFE (high iron) gene contributing to hereditary haemochromatosis can be detected using EUROArray Haemochromatosis Direct test systems. Either two (C282Y, H63D) or four (C282Y, H63D, S65C and E168X) parameters can be analysed in parallel. With both diseases the identification of a predisposition enables early implementation of suitable therapy or preventative measures. The procedure is extremely easy to perform, requiring no previous knowledge of molecular biology. The alleles are analysed directly from whole blood, significantly reducing costs and the hands-on time required. Results are evaluated and documented automatically using the specially developed software. Highly specific primers, ready-to-use PCR components and integrated positive controls all contribute to the reliability of the analysis. All processes are IVD validated and CE registered, and product performance is backed by extensive clinical evaluation data.
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KPL offers next-generation solutions to improve sensitivity and time to results in Western blotting applications. New SignaLOCK™ HRP ChemiWestern Kit (Imager), SignaLOCK HRP ChemiWestern Kit (Film), and SignaLOCK AP ChemiWestern Kit (Film/Imager) enable researchers to reach the highest levels of detection sensitivity. These kits enable detection in the nanogram range with only a 1-minute exposure. A longer exposure offers sensitivity in the femtogram range. The high sensitivity of SignaLOCK kits allows you to use primary and secondary antibodies at higher dilutions, minimizing background and lowering cost. They combine a chemiluminescent substrate with a unique non-protein blocker and wash solution in one powerful system. Whether you prefer peroxidase or phosphatase detection, film or imager analysis, SignaLOCK kits enable researchers to see more signal with less background in their Western blots. All kits offer comprehensive protocols and can be used with both nitrocellulose and PVDF membrane.
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A stand-alone, static urine concentrator that uses a regenerated cellulose membrane to recover more Bence Jones Proteins, giving it a high sensitivity, the UriCon is a self-standing, individual test so there is no cross contamination. Multiples of single devices can be clipped together to allow for a large frequency of daily testing. This device offers unique features such as the luer cap lid to seal the product for improved health and safety. The unique pressure valve can decrease the concentration time of the device even further.
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Covering a total of 15 commonly tested and esoteric cancer antigens and tumour markers, the Acusera multi-analyte liquid tumour marker control is ready to use. The material is highly convenient and easy for laboratory staff. The addition of assayed target values enables laboratories to effectively monitor measurements with both accuracy and precision. The liquid stable nature not only eliminates the need for reconstitution but reduces the amount of human handling necessary and allows the material to be shipped and stored conveniently at 2-8oC. The serum is 100% human in origin providing a matrix similar to the patient sample but also reducing antibody interference and the possibility of control values shifting after changing reagent batch. Three distinct and clinically significant levels of control are available with analytes present at desirable levels. The convenient 6 x 3mL pack size and refrigerated open vial stability of 30 days for all analytes helps to increase laboratory efficiency while keeping waste and costs to a minimum. As a true third party control laboratories can use it to independently assess the performance of their tumour marker testing. Fully assayed, instrument specific target values are generated via a number of external laboratories and are provided for many common clinical chemistry and immunoassay systems. The control is compatible for use with Acusera 24.7, a web based inter-laboratory data management programme. With 24-7 users benefit from the company’s extensive range of data management tools and gain access to peer group data from thousands of laboratories worldwide. The programme uniquely updates peer group data every 24 hours giving laboratories access to the most up to date information available.
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