A groundbreaking customizable immunoassay system developed by Japanese researchers offers rapid detection of disease biomarkers, allergens and other biomolecules with exceptional sensitivity, potentially revolutionising point-of-care diagnostics
A recent report published by the Food Standards Agency in the UK [Patterns and prevalence of adult food allergy (PAFA); https://shorturl.at/jnaLY] estimates that around 6% of the UK adult population have a clinically confirmed IgE-mediated food allergy.
By Dr Jacqueline Gosink New American College of Rheumatology and European Alliance of Associations for Rheumatology classification criteria for antiphospholipid syndrome have been developed to aid cohort selection for research and clinical trials. The classification system includes both clinical and laboratory criteria, which are hierarchically clustered, weighted and risk-stratified to ensure high specificity.
The congenital neutropenia syndromes are rare conditions caused by mutations in genes associated with various cell processes. While their clinical presentations may overlap, their natural histories vary. Accurate diagnosis of the genetic etiology of specific conditions is crucial for providing individually tailored management, as the different syndromes have different risk profiles for progression to bone […]
Tropical infectious diseases such as malaria, cholera, yellow fever, and Dengue affect more than 2 billion people worldwide. Also included in this list are the so-called “Neglected Tropical Diseases” or NTD’s, a sub-group of mainly infectious diseases that occur against a background of extreme poverty. The WHO lists 17 priority Neglected Tropical Diseases, among them […]
It is often said that “necessity is the mother of invention”, something that often seems to happen in war situations. The COVID-19 pandemic, in many ways, felt like a war, and drove fast changes in behaviour, very quickly having us all performing lateral flow tests at home, in a way that could not have been […]
Blood gas analysis for the diagnosis of acid–base disorders is now mainly performed at the point-of-care and the results reported can be affected by a number of factors. Users should be aware of the possible pitfalls to prevent errors in diagnosis and to optimize patient management. CLI chatted to Dr Kate Shipman (Consultant Chemical Pathologist, […]
In a previous article (CLI October 2021 “Diagnosis of acute hepatic porphyria”), we discussed in detail the biochemistry and the diagnosis of the different types of porphyria. Here, we give a brief recap before going on to discuss a recent paper by Gallagher et al. that examined the effects of different specimen storage and handling […]
According to the most recent statistics provided by Cancer Research UK, lung cancer is the third most common cancer in the UK, with around 49 000 new cases in the UK every year which account for 13% of all new cancer cases.
Breast cancer is the most common cancer in females in the UK, with around 56 800 new cases diagnosed every year.
January 2026
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