The geneLEAD VIII, manufactured by PSS and distributed by Diagenode Diagnostics in Europe, is a new all-in-one automated molecular diagnostics platform designed for carrying out small series of tests (1,000 to 4,000 tests/year), from nucleic acid extraction to patient result in 1,5 hour. This instrument can independently perform up to 8 different real-time PCR tests, without or with extraction validated on whole blood, serum, plasma, urine, CSF, swab, sputum and stool. Combining expertise in the development of molecular diagnostic assays acquired over the last 14 years, Diagenode Diagnostics presents here the first in a range of multiplex tests for the geneLEAD VIII, focused on respiratory and gastrointestinal infections, including Influenza A & B virus, together with respiratory syncytial virus (RSV), Mycobacterium tuberculosis complex, Legionella pneumophila & spp, Adenovirus (mid-2019), Bordetella pertussis & parapertussis (late 2019), Norovirus I / II & Rotavirus (late 2019) and Mycoplasma pneumoniae (2020). The geneLEAD VIII is also compatible with Laboratory Developed Tests (LDT) based on real-time PCR and other detection chemistries. The geneLEAD VIII represents a unique CE-IVD solution which is ready for accreditation, easy-to-use and allowing workflow optimization with the middle-to-high-throughput automated systems in molecular diagnostics laboratories.

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The latest addition to the StatStrip line of handheld, hospital meters, the StatStrip Hemoglobin and Hematocrit Meter System (StatStrip Hb/ Hct), has gained CE mark certification and is now available in all CE regulated countries. StatStrip Hb/Hct is the only point-of-care (POC) meter to measure hemoglobin and hematocrit for accurate anemia screening and blood loss monitoring. StatStrip Hb/Hct provides measured hemoglobin and hematocrit results, which are more accurate than calculated results, with excellent correlation to laboratory reference methods. With a fingerstick capillary sample and results in 40 seconds, StatStrip Hb/Hct provides the real-time accuracy that helps improve clinical decision making in a variety of healthcare settings. These include blood banks and temporary blood collection locations, dialysis centres, primary care clinics, hospitals, and oncology clinics. For example, in blood banks, StatStrip Hb/Hct provides safe and effective blood donor screening and avoids false deferrals. For patients receiving dialysis, StatStrip Hb/Hct helps maintain Hb target levels and also monitor erythropoiesis stimulating agents (ESAs) to the lowest effective dose. In emergency care settings and in hospitals, StatStrip Hb/Hct can aid in rapidly evaluating blood loss, initiating treatments more quickly, and monitoring critically ill patients who are at risk for low hemoglobin and hematocrit. In oncology clinics, StatStrip Hb/Hct can help proactively identify patents at high risk for chemotherapy-induced anemia and direct treatment accordingly. StatStrip Hb/Hct’s single-use biosensors do not require calibration or coding, and testing is as easy as glucose self-testing. StatStrip Hb/Hct helps reduce costs by eliminating the need for blood drawing supplies, venous phlebotomy, and laboratory testing. Wired and wireless connectivity for data integration with patient records are available. Compact and lightweight, StatStrip Hb/Hct is less than half the size and weight of other POC systems that measure only hemoglobin.
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The RX series test menu is world leading comprising an extensive range of high quality diagnostic reagents including routine chemistry, specific proteins, lipids, therapeutic drugs, drugs of abuse, antioxidants and diabetes testing.

Superior testing methodologies are available to extend your laboratory’s
testing capabilities. Placing precision, accuracy and reliability at the forefront, the RX series has 29 high performance and novel assays including direct HbA1c testing capabilities.

The RX series clinical chemistry analysers guarantee real cost savings through consolidation
of routine and specialised tests onto one single platform. With a range of semi-automated and automated analysers, the RX series offers versatility to suit the needs of all laboratory requirements.

For more information, visit www.randox.com/rxseries or to speak with your local Randox representative email therxseries@randox.com

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The new Nexera Mikros, a micro flowrate-compatible liquid chromatograph mass spectrometer, maintains the durability and operability of LC-MS systems while providing a significant increase in sensitivity. In pharmaceutical development, analysis occasionally has to be performed on trace amounts only of components in small blood samples. Examples include studies of the pharmacokinetics of new drug substances or their metabolism. In such cases, LC-MS systems compatible with nano flowrates have been utilized, in order to improve the efficiency of the intake of target components to the mass spectrometer. However, nano flowrate-compatible LC-MS systems often suffer from complications in terms of instrument operability and processing speed, such as a tendency for pipes to clog, difficulty in discovering liquid leaks, and the hours required for analysis of a single sample. The Nexera Mikros can accommodate a wide range of flowrates, from semi-micro flowrates (100 to 500 µL/min) which are often used for analysis in existing systems, to micro flowrates (1 to 10 µL/min). With this product, Shimadzu is contributing to improving productivity at pharmaceutical companies and clinical contract research organizations. Nexera Mikros achieves at least ten times the sensitivity for target compounds compared to standard LC-MS analysis. This is due to the LC-Mikros, a solvent delivery pump with a new control system to reduce pulsation and deliver a stable solvent flow even at low micro flowrates. In addition, positioning of the ionization interface has been optimized for more efficient sample introduction into the mass spectrometer.  Another specific feature, UF-Link, achieves both high-sensitivity analysis and improved operability. Microscopic gaps (dead volume) in the piping connectors lead to a decrease in sensitivity by causing peak dispersion. UF-Link, a connection mechanism between Shimadzu’s newly developed analytical column and the mass spectrometer, ensures high sensitivity and, at the same time, enables one-touch connection between the analytical column and the ionization interface for the mass spectrometer. In addition, UF-Link is compatible with connections between commonly used analytical columns and the ionization interface, so column selection is flexible to suit the target sample.

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