Coronaviruses are a group of positive sense, single-stranded RNA viruses that infect humans and animals. In a short period of time the SARS-associated coronavirus was identified and initial laboratory protocols for diagnosis of SARS were disseminated. The need for the early diagnosis of SARS is vital due to the difficulty in clinically diagnosing this infection […]
Simmering concerns about respiratory disease pandemics flared up again in mid-February after the death of a patient in Britain due to infection by a new coronavirus. The virus is part of a family which also includes the one that caused the deadly SARS (severe acute respiratory syndrome) crisis. To recall, in the space of just […]
Primary hepatic tumours are one of the most aggressive and resistant forms of cancer. Early diagnosis of liver cancer and the development of more accurate markers for biological classification are crucial to improving the clinical management and survival of patients. This article discusses the emerging use of microRNAs for the diagnosis of liver cancer. by […]
Optical coherence tomography (OCT) has long been routinely used in ophthalmology, but recent studies in the field of renal cell carcinoma have demonstrated the ability of OCT to distinguish between renal malignancies and normal renal tissue. This suggests the possibility that, eventually, diagnosis by invasive biopsy could be replaced by non-invasive techniques. by D. M. […]
Melanoma is the most malignant type of all skin neoplasms. Although current clinical, morphologic, pathologic, and biochemical methods provide insights into disease behaviour and outcome, melanoma is still an unpredictable disease. Once in an advanced stage, it remains a fatal neoplasm with few therapeutic options. Therefore, significant efforts still need to be made in finding […]
The worldwide prevalence of obesity (defined as a BMI greater than 30) has more than doubled in the last thirty years, largely as a result of lifestyle changes leading to many people having a greater energy intake than expenditure. According to a study published in The Lancet recently, with the exception of populations in sub-Saharan […]
Two novel biochemical tests, the ESBL NDP and the Carba NP tests, have been recently developed for the early detection of ESBL- or carbapenemase resistance traits in Enterobacteriaceae. Those tests are rapid, sensitive, specific and cost-effective. Implementation of those tests in clinical microbiology laboratories may significantly improve the management and outcome of patients. by Dr […]
FilmArray is a highly automated small instrument capable of detecting infectious agents using PCR technology. Due to its simplicity the tests could be performed in a rapid-response core laboratory by general medical technologists. This operational model has demonstrated achievements in reducing turn-around-time and thus improved patient care. by Dr M. Xu, Dr X. Qin, Dr […]
One of the fastest-paced developments in clinical laboratories has been in the area of quality control (QC) systems. Its driver has been the increase in the performance and sophistication of QC software, which has progressively tightened benchmarks for acceptable standards. On the plus side, improved QC systems clearly help a laboratory to serve the needs […]
March 2026
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