Delegates at ECCMID 2015, held in Copenhagen from 25th to 28th April 2015, attended a symposium introducing Beckman Coulter’s new DxN VERIS Molecular Diagnostics System.* DxN VERIS provides a fully automated sample to result platform with true single sample random access, integrating sample introduction, nucleic acid extraction, reaction setup, real-time PCR amplification, detection and results […]
Cervical cancer is a major burden worldwide with significant mortality, especially in developing countries. Human papillomavirus (HPV) analysis is gaining ground as the primary screening modality for the early diagnosis and prevention of cervical carcinoma. Direct pathogen detection allows an infection to be identified before cell changes have even taken place. Thus, interventional measures can […]
Since the mapping of the human genome was completed over a decade ago, our knowledge of genetic drivers of disease continues to evolve at an ever-quickening pace. Consequently, genetic testing and pharmacogenomics have become common within the healthcare system and have generated the knowledge that has empowered us to both understand and influence our lifelong […]
Tumours found in the ovaries can be either from primary ovarian tumour processes or metastases (secondary tumours) foremost from colorectal cancer (CRC), appendiceal tumours or stomach cancer. Correctly distinguishing between these tumour subsets using hematoxylin-eosin staining in combination with immunohistochemistry can be problematic [1–3], but is crucial for correct treatment choice. Mutation profiles, generated in […]
Detection of copy number variations (CNV) in the VHL gene is part of the genetic workup of VHL-related tumours. Current methods for CNV determination have complex workflows and limitations. Digital droplet PCR is a promising methodology that could be used for CNV determination. Its advantages include shorter turnaround time, decreased DNA input and superior precision. […]
Head and neck cancers (HNC) are a globally prevalent malignancy. Despite the efforts of reducing several known etiological factors such as smoking and drinking to lower the incidence of HNC at the population level, the incidence of oropharyngeal cancers (OPC) is on the rise. OPC is caused by human papillomavirus (HPV) and most prevalent in […]
In spite of increased publicity in the Western world about malaria and drives to provide mosquito nets, the disease is still endemic in a large part of the world. This article discusses different methods of malaria diagnosis and the role that point-of-care tests can play in the ultimate goal of malaria elimination. by Dr Jackie […]
March 2026
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