ProBioGen has inked a multi-product commercial license agreement with AstraZeneca to use the GlymaxX technology.
Evonetix, the synthetic biology company bringing semiconductor technology to DNA synthesis, has achieved enzymatic DNA synthesis capability with its proprietary, thermally controlled synthesis chemistry. The culmination of a three-year development programme, supported by Innovate UK and in collaboration with Durham University, the results demonstrate that Evonetix’s unique, semi- conductor array-based platform is compatible with both […]
Centauri Therapeutics, an immunotherapy company founded by Animatrix Founders LLP and focused on the treatment of infectious diseases, has closed a £24 million (US$32 million) Series A investment round. The funds will support the continued advancement of the company’s antimicrobial resistance (AMR) research and development, using the Alphamer platform to identify and progress novel antibacterial […]
German independent research institute BioMed X has started a new research project ‘Advanced Biomarker Detection for Pharma-cological Monitoring in the Brain’ (BDB) in collaboration with Boehringer Ingelheim. The objective of the research group ‘BDB’ is to develop a continuous monitoring biosensor for direct detection of small molecule biomarkers in rodent brain tissue to support the […]
Arctoris, a tech-enabled biopharma company, and Evariste Technologies, an AI-drug discovery company, have formed a joint venture to identify novel small molecule kinase inhibitors for treatment of patients with Non-Small Cell Lung Cancer (NSCLC).
Agilent Technologies says they plan to invest $20 million to expand their Shanghai manufacturing centre to meet growing demand in China for the company’s advanced liquid chromatography (LC), spectrometer and mass spectroscopy (MS) systems.
Despite the enormous success of mumps vaccination campaigns around the world, there has recently been a significant increase in mumps cases and outbreaks in vaccinated populations. As a result, tracking the molecular epidemiology of mumps outbreaks has increased in importance. Here we examine the challenges and limitations associated with traditional molecular genotyping tools and compare […]
In May 2018, a rapid assessment and risk stratification pathway was implemented in Unscheduled Care for patients with suspected acute coronary syndrome, using high-sensitivity (hs) Troponin T. Patients could be ruled out and discharged within one hour of presentation to the Emergency Department. The assay was validated and its safety and clinical effectiveness assured through […]
Selenium (Se) is an essential trace element in many biological processes. Se is measured in many sample matrices. The gold standard Se measurement method is inductively coupled plasma mass spectrometry (ICP-MS). Monitoring alternative isotopes, applying correction factors, and utilizing ICP with a triple quadrupole mass spectrometer are approaches to mitigate the interference of doubly-charged gadolinium.
As interest in vitamins A and E has increased in recent years, so too has the need for rapid and reliable methods by which these compounds can be assayed. The development of a supercritical fluid chromatography–tandem mass spectrometry (SFC-MS/MS)-based method with an automated extraction procedure provides faster analysis than other chromatographic-based methods and improved specificity.
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