Researchers at KAIST have developed a modular organ-on-a-chip platform that recreates the cascade of drug-induced rhabdomyolysis and acute kidney injury in laboratory conditions. The biomicrofluidic system allows muscle and kidney tissues to be connected or separated as needed, enabling precise observation of inter-organ interactions following exposure to medications such as statins and fibrates.
Researchers at the University of Basel have developed a method that measures whether antibiotics truly kill bacteria, not just inhibit their growth. The technique, called Antimicrobial Single-Cell Testing, tracks millions of individual bacterial cells in real time and has demonstrated that a drug’s killing power – rather than growth inhibition alone – predicts treatment success […]
Researchers at Cold Spring Harbor Laboratory have developed a segmented ion accumulation method that significantly improves the sensitivity and dynamic range of mass spectrometry. The innovation, termed HDR-MS1, addresses a fundamental limitation in proteomics research by preventing abundant molecules from overwhelming rare analytes during analysis.
A groundbreaking international study has demonstrated that Alzheimer’s disease biomarkers can be accurately detected using simple finger-prick blood samples collected at home and posted to laboratories without refrigeration. The DROP-AD project, involving 337 participants across seven European centres, found that capillary blood spots could measure key markers including phosphorylated tau 217 (p-tau217) with 86% accuracy […]
Researchers at UC San Diego have developed PanMAN, a novel data structure that compresses pangenomic information up to 1,391 times more efficiently than existing formats whilst simultaneously encoding detailed evolutionary and mutational histories. The technique, published in Nature Genetics, enabled construction of a comprehensive SARS-CoV-2 pangenome from 8 million sequences using just 366 MB of […]
Researchers have engineered a highly accurate CRISPR variant that removes normal DNA before sequencing, enabling detection of circulating tumour DNA at levels as low as 0.005%. The MUTE-Seq method showed promising results in early-stage lung and pancreatic cancer patients, where conventional liquid biopsy often fails.
Cambridge-based biotechnology company Nuclera has completed its first commercial installations in Asia, deploying eProtein Discovery systems at two leading Taiwanese universities. The National Taiwan University and National Cheng Kung University now have access to the benchtop protein production technology, marking a significant milestone in the company’s global expansion.
Revvity has entered into a definitive agreement to acquire ACD/Labs, a global provider of scientific software solutions supporting analytical characterisation and molecular design across pharmaceutical and material sciences sectors.
Chitose Laboratory Corp. and FUJIFILM Biosciences Inc. have formed a strategic alliance to advance biopharmaceutical manufacturing by combining CHO-MK cell line technology with GMP-manufactured culture media. The collaboration aims to enhance production efficiency and support the development of therapeutic solutions for the global pharmaceutical industry.
ProteoNic BV has announced that Ginkgo Bioworks has licensed its proprietary 2G UNic vector technology for a $22.2 million project funded by the Biomedical Advanced Research and Development Authority (BARDA). The initiative aims to enhance domestic biomanufacturing capabilities for monoclonal antibodies targeting filovirus infections, including Ebola and Sudan Virus.
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