The concentration of HbA1c in the blood of diabetic patients increases with rising blood glucose levels and is representative of the mean blood glucose level over the preceding six to eight weeks.

Randox now offers a direct HbA1c assay for the rapid direct measurement of HbA1c in human blood. This assay is available to be used on the RX daytona +, RX imola and RX modena clinical chemistry analysers which are capable of performing medium to high throughput testing. This direct HbA1c test adds to the comprehensive test menu of niche and high performing assays already available at Randox.

The latex enhanced immunoturbidimetric method makes the test simple and quick to perform as only one assay is now required. Human error inaccuracies are removed as offline preparations are no longer required and are preformed on-board the RX series analysers.

For more information about our direct HbA1c assay please visit www.randox.com/hba1c-rxseries/ or contact us at therxseries@randox.com

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The new MALDI-8020 complements Shimadzu’s MALDI family. The linear benchtop time-of-flight mass spectrometer serves various applications in the positive ion mode, such as analysis of proteins, peptides or polymers. It is ideal for researchers developing MALDI-based diagnostic methods, and for routine labs carrying out quality control and fast analysis of intact samples. The MALDI-8020 is fast and accurate, has a high resolution and its compact size makes it fit in any laboratory. The robust design promises reliable analysis and low maintenance. With a mass range of 1-500,000 Da, a mass resolution of more than 5,000 (for ACTH18-39, m/z 2,465), a mass accuracy of < 20 ppm after internal calibration and a sensitivity of 250 amol (Glu-Fib, m/z 1,570), the MALDI-8020 achieves the same specifications as the more advanced version, the Axima Assurance for high throughput screening.  Thanks to its small dimensions of 450 x 745 x 1,055 mm and weight of 86 kg, the new MALDI-8020 fits on any lab workbench. The oil-free diaphragm pump and a turbo pump ensure reliable and low-noise operation (< 55 dB).
Extra-fast motors drive the highspeed stage. Motor installation outside the vacuum reduces the volume to be evacuated, so pumping time after changing of sample is the fastest on the market: around 90 seconds. The 200 Hz solid-state laser allows further optimization of the analysis time. The typical Shimadzu wide-bore ion optics increase ion transmission and reduce the likelihood of contamination. If the source is nevertheless contaminated, it can be cleaned within ten minutes using the UV laser-based TrueClean. The MALDI Solutions software provides intuitive and easy operation, and includes interfaces for evaluating polymer, protein and oligonucleotide spectra. SampleStation, AuraSolution and QC Reporter offer various options for automated lab routines. During sample preparation, data can be collected with the SampleStation software. The barcode reader integrated into the mass spectrometer enables automated measurement using AuraSolution. The QC Reporter software allows specification of different criteria that can be used for automatic evaluation of the analyses. Data is stored in a Microsoft® SQL database with automatic backup. Personalized user logins can be used to document quality control, and different levels can be assigned to individual users. In this way the user is prepared for potential audits.
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The management and control of anticoagulant therapy and the assessment of pre- and post-surgical states require a proper evaluation of the coagulation cascade. Several tests help the physician in the diagnosis of altered coagulation states and management of coagulopathy.
Biosystems offers a range of the most common tests to achieve a complete coagulation profile: Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Fibrinogen Clauss, Thrombin Time (TT), Antithrombin (At III), Total Fibrinogen (based on turbidimetry method) and coming soon DDimer .
PT and Fribrinogen Clauss parameters include a master calibration curve lot by lot; this curve is suitable for all automatic and semiautomatic systems based on mechanical or photo-optical clot detection principles.  This provides significant savings in time and operation costs for laboratories.
The coagulation reagents are manufactured in high quality conditions, providing for PT parameter lot by lot ISI values in the range 1.0-1.1. Thrombin Time and Fibrinogen Clauss parameters are based on human origin Thrombin, achieving the highest reliable results.
The coagulation reagents line is accompanied by a series of semi-automated coagulometers aimed at small to medium size laboratories. The COAX family includes 1, 2 or 4 optical channel devices. Operation is very intuitive, with a high quality colour touchscreen allowing easy patient data management. These devices are optimized for a low consumption of reagents.

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The Flu Typing I kit allows the identification and specific differentiation of Influenza A (H1N1) pdm09 and H3N2 subtypes in respiratory samples from patients with signs and symptoms of respiratory infection.
Currently, Influenza A (H1N1) and Influenza A (H3N2) are the circulating seasonal Influenza A virus subtypes. This seasonal A (H1N1) virus is the same virus that caused the 2009 influenza pandemic. Influenza A (H3N2v) viruses were first detected in patients in 2011, with infections associated with prolonged exposure to pigs at agricultural fairs.
Real-time PCR assays have been shown to be a sensitive and specific diagnostic tool for the detection of the two subtypes of Influenza A (H1N1 and H3N2) that are currently in general circulation among humans.
VIASURE Flu Typing I Real Time PCR Detection Kit contains in each well all the components necessary for real time PCR assay in a stabilized format. RNA is extracted from specimens, amplified using RT-PCR and detected using fluorescent reporter dye probes specific for Influenza A (H1N1)pdm09 and H3N2 subtypes.
In addition, thanks to the lyophilization process, it is possible to send the kit to any part of the world at room temperature without the need for a cold chain or special conditions, as it remains perfectly functional for two years.

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