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Author Archive for: 3wmedia
Entries by 3wmedia
The Ebola Spatial Care Path : point – of – care lessons learned for stopping outbreaks
Ebola profoundly elevated the impact of point-of-care testing, now recognized worldwide as essential to detect the disease, reduce risk, monitor patients in isolation, achieve recovery, and importantly, contain outbreaks. The goal is to become resilient – a new and possibly more contagious threat might appear. We must stop it where it starts! by Prof. G. […]
Sound diagnostics: rapid point-of-care nucleic-acid based tests for sexually transmitted infections
One of the major avenues for addressing the rising impact of sexually transmitted infections lies with rapid, early diagnosis to break the cycle of transmission. Here we discuss the potential of a new technology, using the mechanical energy of sound waves, to drive integrated point-of-care diagnostics. by Dr Julien Reboud, Gaolian Xu and Prof. Jonathan […]
New standards, clinical pathways required to maximize benefits
Point-of-care testing (POCT or POC testing) describes diagnostic tests which are performed at or physically close to a patient. This distinguishes POCT from traditional testing, which involves extracting specimens from a patient and transporting them to a laboratory for analysis. Settings for POC tests range from in-hospital bed sites and primary care offices to patient […]
Point-of-care diagnostics for malaria
In spite of increased publicity in the Western world about malaria and drives to provide mosquito nets, the disease is still endemic in a large part of the world. This article discusses different methods of malaria diagnosis and the role that point-of-care tests can play in the ultimate goal of malaria elimination. by Dr Jackie […]
Tumour markers for oropharyngeal cancers
Head and neck cancers (HNC) are a globally prevalent malignancy. Despite the efforts of reducing several known etiological factors such as smoking and drinking to lower the incidence of HNC at the population level, the incidence of oropharyngeal cancers (OPC) is on the rise. OPC is caused by human papillomavirus (HPV) and most prevalent in […]
Detection of von Hippel–Lindau (VHL) gene copy number variation
Detection of copy number variations (CNV) in the VHL gene is part of the genetic workup of VHL-related tumours. Current methods for CNV determination have complex workflows and limitations. Digital droplet PCR is a promising methodology that could be used for CNV determination. Its advantages include shorter turnaround time, decreased DNA input and superior precision. […]
Diagnostically challenging cases: distinguishing primary from secondary ovarian tumours
Tumours found in the ovaries can be either from primary ovarian tumour processes or metastases (secondary tumours) foremost from colorectal cancer (CRC), appendiceal tumours or stomach cancer. Correctly distinguishing between these tumour subsets using hematoxylin-eosin staining in combination with immunohistochemistry can be problematic [1–3], but is crucial for correct treatment choice. Mutation profiles, generated in […]