Barrett’s esophagus has been established as a pre-cancerous condition that increases an individual’s risk of developing esophageal cancer, and so regular monitoring people with Barrett’s esophagus can help improve the survival rates of those who develop cancer. However, diagnosis is usually by endoscopy, which is invasive, unpleasant and resource-intensive. CLI caught up with Charlene Tang […]
Thiopurine pharmacogenomics and pregnancy in inflammatory bowel disease Andoh A, Kawahara M, Imai T, et al. J Gastroenterol 2021; 56(10): 881–890 The thiopurine drugs azathioprine and 6-mercaptopurine are widely used for the maintenance of clinical remission in steroid-dependent inflammatory bowel disease (IBD). Thiopurines are recommended to be continued throughout pregnancy in IBD patients, but conclusive […]
The COVID-19 outbreak caused by severe acute respiratory syndrome virus 2 (SARS-CoV-2) that was declared a pandemic in March 2020 has resulted in a the development of diagnostic tests and vaccines at an unprecedented speed. The development of de novo therapeutics, though, takes considerably longer, which is where the repurposing of existing drugs is being […]
The COVID-19 pandemic has reinforced the critical importance of diagnosis and access to these services, both at the individual and at a population level. The pandemic has also impacted the delivery of diagnostics and care for other medical conditions, such as HIV/AIDS, but similarly, lessons learned with COVID-19 can also be applied to improve diagnostic […]
Despite rapid advances in the areas of genomics and digital image analysis, cancer diagnosis remains largely reliant on tissue/cellular morphological assessment by an expert pathologist. Here, we summarize a newly developed approach to histology, based on a plasmon-induced colour change which provides instant, label-free visualization (or contrast) of cancer cells, distinguishing them from other cells […]
Leading researchers are warning of the dangers of a quiet epidemic of vitamin B12 deficiency in people who follow increasingly popular plant-based diets and explain how it can be addressed.
Microplastics – tiny pieces of plastic less than 5 mm in length – are everywhere, from bottled water to food to air. They have been found in the deepest part of the ocean and the top of Mount Everest. According to recent estimates, people consume tens of thousands of these particles each year, with unknown […]
A common strategy to make vaccines more powerful is to deliver them along with an adjuvant – a compound that stimulates the immune system to produce a stronger response.
To solve the mysteries of how learning and memory occur, Johns Hopkins Medicine scientists have created a system to track millions of connections among brain cells in mice – all at the same time – when the animals’ whiskers are tweaked, an indicator for learning.
Ziath has introduced Cyclops – a new linear and 2D barcode reader for its popular DataPaq Mirage, Cube and Express rack readers.
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